IL7R Products
(Interleukin 7 Receptor (IL7R))
Categories
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008].
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Featured IL7R Categories
IL7R Antibodies
High quality antibodies with extensive validation data.
IL7R ELISA Kits
Reliable ELISA kits for a wide range of species.
IL7R Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL7R Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (7)
Cat. No.
ABIN7434320
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, ELISA
Validations
- (5)
Cat. No.
ABIN7193312
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7156926
Quantity
100 μL
Datasheet
Datasheet
Recommended IL7R ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968025
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957181
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957182
Quantity
96 tests
Datasheet
Datasheet
Recommended IL7R Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274965
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274967
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274964
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL7R products
: "Influence of glucose and insulin in human adipogenic differentiation models with adipose-derived stem cells." in: Adipocyte, Vol. 8, Issue 1, pp. 254-264, (2019) (PubMed).: "Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques." in: PLoS ONE, Vol. 12, Issue 12, pp. e0188427, (2018) (PubMed).
: "Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006425, (2017) (PubMed).
: "Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+subset." in: Journal of leukocyte biology, Vol. 102, Issue 6, pp. 1289-1298, (2017) (PubMed).
: "DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2861-9, (2015) (PubMed).
: "Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 520-8, (2014) (PubMed).
: "IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein." in: PLoS ONE, Vol. 9, Issue 7, pp. e102677, (2014) (PubMed).
: "Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease." in: Blood, Vol. 124, Issue 5, pp. 812-21, (2014) (PubMed).
: "High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer." in: Cancer research, Vol. 74, Issue 8, pp. 2204-16, (2014) (PubMed).
: "An immunological biomarker to predict MTX response in early RA." in: Annals of the rheumatic diseases, Vol. 73, Issue 11, pp. 2047-53, (2014) (PubMed).
Synonyms and alternative names related to IL7R
interleukin 7 receptor (IL7R), interleukin 7 receptor (Il7r), CD127, CDW127, IL-7R-alpha, IL-7RA, IL-7Ralpha, IL7R, IL7RA, ILRAProtein level used designations for IL7R
- interleukin 7 receptor
- interleukin-7 receptor subunit alpha-like
- IL-7 receptor alpha chain
- IL-7 receptor subunit alpha
- IL-7R subunit alpha
- IL-7R-alpha
- IL-7RA
- interleukin 7 receptor alpha chain
- interleukin-7 receptor subunit alpha
- CD127 antigen
- interleukin 7 receptor isoform H5-6
- Interleukin-7 receptor subunit alpha-like protein
- Interleukin-7 receptor subunit alpha
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