IL5RA Products
(Interleukin 5 Receptor, alpha (IL5RA))
Categories
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011].
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Featured IL5RA Categories
IL5RA Antibodies
High quality antibodies with extensive validation data.
IL5RA ELISA Kits
Reliable ELISA kits for a wide range of species.
IL5RA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL5RA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7433729
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN7193317
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7433726
Quantity
100 μL
Datasheet
Datasheet
Recommended IL5RA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957164
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957165
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730708
Quantity
96 tests
Datasheet
Datasheet
Recommended IL5RA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275035
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275042
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275023
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL5RA products
: "Catalpol alleviates ovalbumin-induced asthma in mice: Reduced eosinophil infiltration in the lung." in: International immunopharmacology, Vol. 43, pp. 140-146, (2016) (PubMed).: "Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling." in: The Journal of biological chemistry, Vol. 286, Issue 46, pp. 40091-103, (2011) (PubMed).
: "Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties." in: Journal of leukocyte biology, Vol. 89, Issue 2, pp. 311-7, (2011) (PubMed).
: "Separate endocytic pathways regulate IL-5 receptor internalization and signaling." in: Journal of leukocyte biology, Vol. 84, Issue 2, pp. 499-509, (2008) (PubMed).
: "Identification of UNC119 as a novel activator of SRC-type tyrosine kinases." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8837-45, (2003) (PubMed).
: "T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta." in: The Journal of allergy and clinical immunology, Vol. 110, Issue 4, pp. 624-33, (2002) (PubMed).
Synonyms and alternative names related to IL5RA
interleukin 5 receptor subunit alpha L homeolog (il5ra.L), interleukin 5 receptor subunit alpha (IL5RA), interleukin 5 receptor subunit alpha (il5ra), interleukin 5 receptor subunit alpha (Il5ra), interleukin 5 receptor, alpha (Il5ra), CD125, cdw125, CDw125, gpIL-5ra, hsil5r3, HSIL5R3, il5r, IL5R, Il5r, IL5RA, MGC86517Protein level used designations for IL5RA
- interleukin 5 receptor, alpha
- Interleukin-5 receptor subunit alpha
- interleukin-5 receptor subunit alpha
- interleukin 5 receptor alpha
- interleukin-5 receptor, alpha
- interleukin-5 receptor subunit alpha-like
- CD125 antigen
- IL-5 receptor subunit alpha
- IL-5R subunit alpha
- interleukin 5 receptor type 3
- interleukin-5 receptor alpha chain
- IL-5 receptor alpha chain
- IL-5R-alpha
- IL-5RA
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