IL3RA Products
(Interleukin 3 Receptor, alpha (IL3RA))
Categories
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012].
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Featured IL3RA Categories
IL3RA Antibodies
High quality antibodies with extensive validation data.
IL3RA ELISA Kits
Reliable ELISA kits for a wide range of species.
IL3RA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL3RA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, IHC, ELISA, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN1724855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (3)
- (4)
Cat. No.
ABIN1176839
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ISt, StM
Validations
- (5)
Cat. No.
ABIN6939783
Quantity
100 μg
Datasheet
Datasheet
Recommended IL3RA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957129
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883419
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730726
Quantity
96 tests
Datasheet
Datasheet
Recommended IL3RA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274943
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274946
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274938
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL3RA products
: "Aerobic exercise in humans mobilizes HSCs in an intensity-dependent manner." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 122, Issue 1, pp. 182-190, (2017) (PubMed).: "Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells." in: Oncotarget, Vol. 6, Issue 7, pp. 5354-68, (2016) (PubMed).
: "The composition of cellular infiltrates in anti-HMG-CoA reductase-associated myopathy." in: Muscle & nerve, Vol. 52, Issue 2, pp. 189-95, (2015) (PubMed).
: "Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123938, (2015) (PubMed).
: "Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody." in: Cell reports, Vol. 8, Issue 2, pp. 410-9, (2014) (PubMed).
: "Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R." in: PLoS ONE, Vol. 9, Issue 1, pp. e84417, (2014) (PubMed).
: "Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 13, pp. 3589-602, (2014) (PubMed).
: "Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol." in: Frontiers in oncology, Vol. 3, pp. 118, (2013) (PubMed).
: "A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis." in: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2939-50, (2013) (PubMed).
: "IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study." in: PLoS ONE, Vol. 6, Issue 11, pp. e27351, (2011) (PubMed).
Synonyms and alternative names related to IL3RA
interleukin 3 receptor subunit alpha (IL3RA), interleukin 3 receptor, alpha chain (Il3ra), interleukin 3 receptor subunit alpha (Il3ra), CD123, CDw123, Cyrl, hIL-3Ra, IL3R, IL3RAY, IL3RX, IL3RY, SUT-1Protein level used designations for IL3RA
- CD123 antigen
- IL-3 receptor alpha SP2 isoform
- IL-3 receptor subunit alpha
- IL-3R subunit alpha
- IL-3R-alpha
- IL-3RA
- interleukin-3 receptor subunit alpha
- IL-3 receptor alpha chain
- Il-3 alpha subunit
- interleukin-3 receptor class II alpha chain
- cytokine receptor-like protein CYRL
- interleukin 3 receptor, alpha chain
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