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IL2RG Products

(Interleukin 2 Receptor, gamma (IL2RG))

Categories

The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010].

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Featured IL2RG Categories

IL2RG Antibodies

High quality antibodies with extensive validation data.

IL2RG ELISA Kits

Reliable ELISA kits for a wide range of species.

IL2RG Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL2RG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, FACS, ELISA
Validations
  • (5)
Cat. No. ABIN2176981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IF
Validations
  • (5)
Cat. No. ABIN653403
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN7193309
Quantity 100 μL
Datasheet Datasheet

Recommended IL2RG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957091
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951312
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN5069134
Quantity 96 tests
Datasheet Datasheet

Recommended IL2RG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274070
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274089
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274078
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL2RG products

Kuca-Warnawin, Kurowska, Prochorec-Sobieszek, Radzikowska, Burakowski, Skalska, Massalska, Plebańczyk, Małdyk-Nowakowska, Słowińska, Gasik, Maśliński: "Rheumatoid arthritis bone marrow environment supports Th17 response." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 274, (2018) (PubMed).

Jiang, Chen, An, Yang, Zhang, Cheng: "Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling." in: Scientific reports, Vol. 6, pp. 32320, (2016) (PubMed).

Assirelli, Pulsatelli, Dolzani, Platano, Olivotto, Filardo, Trisolino, Facchini, Borzì, Meliconi et al.: "Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading ..." in: PLoS ONE, Vol. 9, Issue 5, pp. e96925, (2015) (PubMed).

Dupuy, Lambert, Zucman, Choukem, Tognarelli, Pages, Lebbé, Caillat-Zucman: "Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma." in: PLoS pathogens, Vol. 8, Issue 1, pp. e1002486, (2012) (PubMed).

Mujib, Jones, Lo, Aidarus, Clayton, Sakhdari, Benko, Kovacs, Ostrowski et al.: "Antigen-independent induction of Tim-3 expression on human T cells by the common ?-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 8, pp. 3745-56, (2012) (PubMed).

Giron-Michel, Azzi, Khawam, Mortier, Caignard, Devocelle, Ferrini, Croce, François, Lecru, Charpentier, Chouaib, Azzarone, Eid: "Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway." in: PLoS ONE, Vol. 7, Issue 2, pp. e31624, (2012) (PubMed).

Pandya, Al-Jaderi, Høglund, Holmøy, Harbo, Norgauer, Maghazachi: "Identification of human NK17/NK1 cells." in: PLoS ONE, Vol. 6, Issue 10, pp. e26780, (2011) (PubMed).

Rose, Pillet, Lavergne, Tamarit, Lenormand, Rousselle, Namane, Thèze: "Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response." in: The Journal of biological chemistry, Vol. 285, Issue 20, pp. 14898-908, (2010) (PubMed).

Rose, Lambotte, Pallier, Delfraissy, Colle: "Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7389-97, (2009) (PubMed).

Ogbomo, Michaelis, Altenbrandt, Doerr, Cinatl: "A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function." in: Biochemical pharmacology, Vol. 79, Issue 2, pp. 188-97, (2009) (PubMed).

Synonyms and alternative names related to IL2RG

interleukin 2 receptor subunit gamma (IL2RG), interleukin 2 receptor subunit gamma L homeolog (il2rg.L), interleukin 2 receptor subunit gamma (Il2rg), interleukin 2 receptor, gamma chain (Il2rg), Ab2-183, Cd132, CD132, CIDX, gamma(c), gc, IL-2RG, IMD4, P64, SCIDX, SCIDX1, [g]c

Protein level used designations for IL2RG

  • cytokine receptor common subunit gamma
  • interleukin 2 receptor gamma
  • interleukin 2 receptor, gamma (severe combined immunodeficiency)
  • membrane receptor Il2rg
  • interleukin 2 receptor, gamma
  • CD132 antigen
  • IL-2 receptor subunit gamma
  • IL-2R subunit gamma
  • common cytokine receptor gamma chain
  • gammaC
  • IL-2R gamma chain
  • IL-2RG
  • cytokine receptor common gamma chain
  • gamma-C
  • interleukin-2 receptor gamma chain
  • interleukin-2 receptor subunit gamma
  • p64
  • interleukin 2 receptor gamma chain
  • common gamma chain
  • gamma C receptor
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