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IL28B Products

(Interleukin 28B (Interferon, lambda 3) (IL28B))
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008].

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Featured IL28B Categories

IL28B Antibodies

High quality antibodies with extensive validation data.

IL28B ELISA Kits

Reliable ELISA kits for a wide range of species.

IL28B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL28B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN1539309
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7261598
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7156612
Quantity 100 μL
Datasheet Datasheet

Recommended IL28B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6957123
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6999469
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730793
Quantity 96 tests
Datasheet Datasheet

Recommended IL28B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7455683
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505166
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505419
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL28B products

Cakmak Genc, Dursun, Karakas Celik, Calik, Kokturk, Piskin: "IL28B, IL29 and micro-RNA 548 in subacute sclerosing panencephalitis as a rare disease." in: Gene, Vol. 678, pp. 73-78, (2018) (PubMed).

Ferraris, Chandra, Panigrahi, Aboulnasr, Chava, Kurt, Pawlotsky, Wilkens, Osterlund, Hartmann, Balart, Wu, Dash: "Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression." in: The American journal of pathology, Vol. 186, Issue 4, pp. 938-51, (2016) (PubMed).

Hoffmann, Schmidt, Dittmann Chevillotte, Wisskirchen, Hellmuth, Willms, Gilmore, Glas, Folwaczny, Müller, Berg, Spengler, Fitzmaurice, Kelleher, Reisch, Rice, Endres, Rothenfusser: "Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 2, pp. 460-70, (2015) (PubMed).

Grygorczuk, Parczewski, Moniuszko, ?wierzbi?ska, Kondrusik, Zajkowska, Czupryna, Dunaj, Boro?-Kaczmarska, Pancewicz: "Increased concentration of interferon lambda-3, interferon beta and interleukin-10 in the cerebrospinal fluid of patients with tick-borne encephalitis." in: Cytokine, Vol. 71, Issue 2, pp. 125-31, (2015) (PubMed).

Resham, Manzoor, Imran, Saalim, Naseem, Azam: "Interleukin- 28B: a prognostic marker in interferon based therapy of chronic HCV patients of the Pakistan with variable treatment response." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 123, Issue 9, pp. 765-71, (2015) (PubMed).

Khairy, Fouad, Mabrouk, El-Akel, Awad, Salama, Elnegouly, Shaker et al.: "The impact of interleukin 28b gene polymorphism on the virological response to combined pegylated interferon and ribavirin therapy in chronic HCV genotype 4 infected egyptian patients using data ..." in: Hepatitis monthly, Vol. 13, Issue 7, pp. e10509, (2013) (PubMed).

Kanda, Jiang, Nakamoto, Nakamura, Miyamura, Wu, Yokosuka: "Different effects of three interferons L on Toll-like receptor-related gene expression in HepG2 cells." in: Cytokine, Vol. 64, Issue 2, pp. 577-83, (2013) (PubMed).

Rallón, Soriano, Naggie, Restrepo, McHutchison, Vispo, Benito: "Impact of IL28B gene polymorphisms on interferon-?3 plasma levels during pegylated interferon-?/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV." in: The Journal of antimicrobial chemotherapy, Vol. 67, Issue 5, pp. 1246-9, (2012) (PubMed).

Synonyms and alternative names related to IL28B

interferon, lambda 3 (Ifnl3), interferon lambda 3 (IFNL3), interferon lambda 3 (Ifnl3), IFL-1, IL-28B, Il28, Il28b, IL28B, IL28C, INF-alpha, INF-lambda

Protein level used designations for IL28B

  • interleukin 28B
  • interleukin-29
  • IFN-lambda-3
  • interferon alpha
  • interferon lambda-3
  • interleukin 28
  • interleukin-28B
  • IFN-lambda-4
  • IL-28C
  • cytokine Zcyto22
  • interferon lambda-4
  • interferon, lambda 4
  • interleukin 28B (interferon, lambda 3)
  • interleukin 28C
  • interleukin-28C
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