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IL1RN Proteins

(Interleukin 1 Receptor Antagonist (IL1RN))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
IL1RN Protein (AA 1-159) (GST tag) IL1RN Protein (AA 1-159) (GST tag) IL1RN Protein (AA 1-159) (GST tag) (ABIN1307765)

IL1RN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

IL1RN Protein (ABIN988019)

IL1RN Origin: Human Host: Escherichia coli (E. coli) > 95 % by SDS-PAGE and HPLC analyses. Active

IL1RN Protein (AA 25-178) (His tag) IL1RN Protein (AA 25-178) (His tag) IL1RN Protein (AA 25-178) (His tag) (ABIN7123525)

IL1RN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

IL1RN Proteins by Origin

Find IL1RN Proteins for a variety of species such as anti-Human IL1RN, anti-Mouse IL1RN, anti-Dog IL1RN. The species listed below are among those available. Click on a link to go to the corresponding products.

IL1RN Proteins by Source

Here you will find IL1RN Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IL1RN Proteins by Protein Type

Here you can find IL1RN Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IL1RN Proteins by Application

Find IL1RN Proteins validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL1RN Proteins by Biological Activity

Find IL1RN Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular IL1RN Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307765
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN988019
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123525
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964205
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320549
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
Cat. No. ABIN2017978
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505391
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7504980
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319570
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1111703
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
Cat. No. ABIN7505735
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7533698
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389482
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN4371455
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389491
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL1RN Proteins

Wang, Zhen, Fan, Qin, Han, Zhou, Wang, An: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." in: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hunt, Xu, Finkelstein, Fan, Carroll, Cheng, Eisenman, Demontis: "The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling." in: Genes & development, Vol. 29, Issue 23, pp. 2475-89, (2015) (PubMed).

Hedl, Abraham: "Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines." in: Gastroenterology, Vol. 143, Issue 6, pp. 1530-43, (2012) (PubMed).

Hedl, Abraham: "Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26440-9, (2011) (PubMed).

OShaughnessy, Choudhary, Harper: "Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2594-605, (2010) (PubMed).

Eisenberg, Brewer, Verderber, Heimdal, Brandhuber, Thompson: "Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 12, pp. 5232-6, (1991) (PubMed).

Carter, Deibel, Dunn, Tomich, Laborde, Slightom, Berger, Bienkowski, Sun, McEwan: "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein." in: Nature, Vol. 344, Issue 6267, pp. 633-8, (1990) (PubMed).

Aliases for IL1RN Proteins

interleukin 1 receptor antagonist (IL1RN) Proteins
interleukin 1 receptor antagonist (Il1rn) Proteins
interleukin 1 receptor antagonist-like (IL1RNL) Proteins
DIRA Proteins
F630041P17Rik Proteins
ICIL-1RA Proteins
IL-1ra Proteins
IL-1RA Proteins
IL-1ra3 Proteins
IL-1RN Proteins
IL1F3 Proteins
IL1RA Proteins
IL1RN Proteins
IRAP Proteins
IRAP1 Proteins
MVCD4 Proteins
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