IL1RN Products
(Interleukin 1 Receptor Antagonist (IL1RN))
Categories
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured IL1RN Categories
IL1RN Antibodies
High quality antibodies with extensive validation data.
IL1RN ELISA Kits
Reliable ELISA kits for a wide range of species.
IL1RN Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL1RN Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ICC, IF, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN2856394
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7431371
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7425773
Quantity
100 μL
Datasheet
Datasheet
Recommended IL1RN ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6956957
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956955
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956958
Quantity
96 tests
Datasheet
Datasheet
Recommended IL1RN Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1307765
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN988019
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123525
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IL1RN products
: "Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study. ..." in: The Lancet. Rheumatology, Vol. 4, Issue 5, pp. e329-e337, (2022) (PubMed).: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." in: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).
: "A similar pro/anti-inflammatory cytokine balance is present in the airways of competitive athletes and non-exercising asthmatics." in: Advances in medical sciences, Vol. 63, Issue 1, pp. 79-86, (2018) (PubMed).
: "Interleukin 1 receptor antagonist and 2'-5'-oligoadenylate synthetase-like molecules as novel biomarkers for multiple sclerosis patients in Bahrain." in: Multiple sclerosis and related disorders, Vol. 18, pp. 1-7, (2018) (PubMed).
: "Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure." in: Diabetes Care, Vol. 41, Issue 4, pp. 823-830, (2018) (PubMed).
: "The effect of salusin-β on expression of pro- and anti-inflammatory cytokines in human umbilical vein endothelial cells (HUVECs)." in: ARYA atherosclerosis, Vol. 14, Issue 1, pp. 1-10, (2018) (PubMed).
: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "Winter ambient training conditions are associated with increased bronchial hyperreactivity and with shifts in serum innate immunity proteins in young competitive speed skaters." in: Archives of medical science : AMS, Vol. 14, Issue 1, pp. 60-68, (2018) (PubMed).
: "Effect of interleukin-1β on occludin mRNA expression in the duodenal and colonic mucosa of dogs with inflammatory bowel disease." in: Journal of veterinary internal medicine, Vol. 32, Issue 3, pp. 1019-1025, (2018) (PubMed).
: "Cholesterol crystals enhance TLR2- and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis." in: PLoS ONE, Vol. 12, Issue 2, pp. e0172773, (2017) (PubMed).
Synonyms and alternative names related to IL1RN
interleukin 1 receptor antagonist (IL1RN), interleukin 1 receptor antagonist (Il1rn), interleukin 1 receptor antagonist-like (IL1RNL), DIRA, F630041P17Rik, ICIL-1RA, IL-1ra, IL-1RA, IL-1ra3, IL-1RN, IL1F3, IL1RA, IL1RN, IRAP, IRAP1, MVCD4Protein level used designations for IL1RN
- IL1 inhibitor
- IL1RN (IL1F3)
- interleukin-1 receptor antagonist protein
- intracellular IL-1 receptor antagonist type II
- intracellular interleukin-1 receptor antagonist (icIL-1ra)
- type II interleukin-1 receptor antagonist
- IL-1RN
- IL-1ra
- IRAP
- interleukin 1 receptor antagonist
- interleukin-1 receptor antagonist secretory form
- secretory interleukin-1 receptor antagonist
- IL-1 receptor antagonist
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