IL1RAP Products
(Interleukin 1 Receptor Accessory Protein (IL1RAP))
Categories
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009].
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Featured IL1RAP Categories
IL1RAP Antibodies
High quality antibodies with extensive validation data.
IL1RAP ELISA Kits
Reliable ELISA kits for a wide range of species.
IL1RAP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL1RAP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7438568
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7436570
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN6242411
Quantity
50 μL
Datasheet
Datasheet
Recommended IL1RAP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN6730975
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956952
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883354
Quantity
96 tests
Datasheet
Datasheet
Recommended IL1RAP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274904
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275029
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274905
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL1RAP products
: "Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling." in: iScience, Vol. 25, Issue 7, pp. 104508, (2022) (PubMed).: "Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling." in: Structure (London, England : 1993), Vol. 27, Issue 8, pp. 1296-1307.e5, (2020) (PubMed).
: "CML Hematopoietic Stem Cells Expressing IL1RAP Can Be Targeted by Chimeric Antigen Receptor-Engineered T Cells." in: Cancer research, Vol. 79, Issue 3, pp. 663-675, (2019) (PubMed).
: "SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 20, pp. E4002-E4009, (2017) (PubMed).
: "Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia." in: Clinical and experimental immunology, (2015) (PubMed).
: "Blood soluble interleukin 1 receptor accessory protein levels are consistently low throughout the menstrual cycle of women with endometriosis." in: Reproductive biology and endocrinology : RB&E, Vol. 12, pp. 51, (2014) (PubMed).
: "IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma." in: Biochemical and biophysical research communications, Vol. 426, Issue 1, pp. 116-21, (2012) (PubMed).
: "Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS." in: Blood, Vol. 120, Issue 6, pp. 1290-8, (2012) (PubMed).
: "Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity." in: The Journal of biological chemistry, Vol. 285, Issue 27, pp. 20607-14, (2010) (PubMed).
: "Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts." in: Gut, Vol. 59, Issue 4, pp. 531-41, (2010) (PubMed).
Synonyms and alternative names related to IL1RAP
interleukin 1 receptor accessory protein (IL1RAP), interleukin 1 receptor accessory protein (il1rap), interleukin 1 receptor accessory protein (il-1racp), interleukin 1 receptor accessory protein (Il1rap), 6430709H04Rik, AI255955, AV239853, C3orf13, il-1racp, IL-1RAcP, IL-1RAcp, il-racp, il1r3, IL1R3, Il1racpb, IL1RAPProtein level used designations for IL1RAP
- interleukin 1 receptor accessory protein
- interleukin-1 receptor accessory protein
- interleukin-1 receptor accessory protein-like
- IL-1 receptor accessory protein
- IL-1R3
- interleukin-1 receptor 3
- interleukin-1 receptor accessory protein beta
- IL-1RAcP
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