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IL1R2 Products

(Interleukin 1 Receptor, Type II (IL1R2))

Categories

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012].

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Featured IL1R2 Categories

IL1R2 Antibodies

High quality antibodies with extensive validation data.

IL1R2 ELISA Kits

Reliable ELISA kits for a wide range of species.

IL1R2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL1R2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN747758
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN2856630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN521667
Quantity 50 μg
Datasheet Datasheet

Recommended IL1R2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956964
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956965
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967812
Quantity 96 tests
Datasheet Datasheet

Recommended IL1R2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274894
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274888
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274910
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL1R2 products

Spano, Grisendi, Golinelli, Rossignoli, Prapa, Bestagno, Candini, Petrachi, Recchia, Miselli, Rovesti, Orsi, Maiorana, Manni, Veronesi, Piccinno, Murgia, Pinelli, Horwitz, Cascinu, Conte, Dominici: "Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 1788, (2019) (PubMed).

Shin, Kim, Lee, Kim: "TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats." in: BMC neuroscience, Vol. 20, Issue 1, pp. 45, (2019) (PubMed).

Lang, Jiang, Gao, Wang, Wang, Wang, Zhang, Chen, Liu, Liu, Yang, Xiao: "Interleukin-1 Receptor 2: A New Biomarker for Sepsis Diagnosis and Gram-Negative/Gram-Positive Bacterial Differentiation." in: Shock (Augusta, Ga.), Vol. 47, Issue 1, pp. 119-124, (2018) (PubMed).

Martin, Palmer, Rodriguez, Seemayer, Palomo, Talabot-Ayer, Gabay: "Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 7, pp. 2916-2926, (2017) (PubMed).

Walscheid, Weinhage, Foell, Heinz, Kasper, Heiligenhaus: "Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis." in: Clinical immunology (Orlando, Fla.), (2016) (PubMed).

Vasilyev, Silkov, Sennikov: "Relationship between interleukin-1 type 1 and 2 receptor gene polymorphisms and the expression level of membrane-bound receptors." in: Cellular & molecular immunology, Vol. 12, Issue 2, pp. 222-30, (2015) (PubMed).

Alshevskaya, Lopatnikova, Shkaruba, Chumasova, Sizikov, Karaulov, Kozlov, Sennikov: "Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis." in: Mediators of inflammation, Vol. 2015, pp. 948393, (2015) (PubMed).

Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).

Asaoka, Island, Tryphonopoulos, Selvaggi, Moon, Tekin, Amador, Levi, Garcia, Smith, Nishida, Weppler, Tzakis, Ruiz: "Characteristic immune, apoptosis and inflammatory gene profiles associated with intestinal acute cellular rejection in formalin-fixed paraffin-embedded mucosal biopsies." in: Transplant international : official journal of the European Society for Organ Transplantation, Vol. 24, Issue 7, pp. 697-707, (2011) (PubMed).

Sekigawa, Tajima, Hasegawa, Hasegawa, Inoue, Sano, Matsune, Kurono, Inoue: "Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma." in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 39, Issue 7, pp. 972-81, (2009) (PubMed).

Synonyms and alternative names related to IL1R2

interleukin 1 receptor type 2 (IL1R2), interleukin 1 receptor, type II (Il1r2), interleukin 1 receptor type 2 (Il1r2), interleukin-like (KK34), CD121b, CDw121b, IL-1R-2, IL-1R2, IL-1RT-2, IL-1RT2, Il1r-2, IL1R2c, IL1RB

Protein level used designations for IL1R2

  • CD121 antigen-like family member B
  • IL-1 type II receptor
  • IL-1R-beta
  • antigen CDw121b
  • interleukin 1 receptor type II variant 3
  • interleukin-1 receptor beta
  • interleukin-1 receptor type 2
  • interleukin-1 receptor type II
  • type II interleukin-1 receptor, beta
  • IL-1 receptor beta chain
  • IL-1R-2
  • IL-1RT-2
  • IL-1RT2
  • soluble type II IL-1 receptor
  • interleukin 1 receptor, type II
  • IL-1 receptor 2
  • interleukin 1 receptor, beta
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