IL1R2 Products
(Interleukin 1 Receptor, Type II (IL1R2))
Categories
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012].
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Featured IL1R2 Categories
IL1R2 Antibodies
High quality antibodies with extensive validation data.
IL1R2 ELISA Kits
Reliable ELISA kits for a wide range of species.
IL1R2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL1R2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN747758
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2856630
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (4)
Cat. No.
ABIN521667
Quantity
50 μg
Datasheet
Datasheet
Recommended IL1R2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956964
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956965
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967812
Quantity
96 tests
Datasheet
Datasheet
Recommended IL1R2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274894
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274888
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274910
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL1R2 products
: "Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 1788, (2019) (PubMed).: "TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats." in: BMC neuroscience, Vol. 20, Issue 1, pp. 45, (2019) (PubMed).
: "Interleukin-1 Receptor 2: A New Biomarker for Sepsis Diagnosis and Gram-Negative/Gram-Positive Bacterial Differentiation." in: Shock (Augusta, Ga.), Vol. 47, Issue 1, pp. 119-124, (2018) (PubMed).
: "Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 7, pp. 2916-2926, (2017) (PubMed).
: "Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis." in: Clinical immunology (Orlando, Fla.), (2016) (PubMed).
: "Relationship between interleukin-1 type 1 and 2 receptor gene polymorphisms and the expression level of membrane-bound receptors." in: Cellular & molecular immunology, Vol. 12, Issue 2, pp. 222-30, (2015) (PubMed).
: "Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis." in: Mediators of inflammation, Vol. 2015, pp. 948393, (2015) (PubMed).
: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).
: "Characteristic immune, apoptosis and inflammatory gene profiles associated with intestinal acute cellular rejection in formalin-fixed paraffin-embedded mucosal biopsies." in: Transplant international : official journal of the European Society for Organ Transplantation, Vol. 24, Issue 7, pp. 697-707, (2011) (PubMed).
: "Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma." in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 39, Issue 7, pp. 972-81, (2009) (PubMed).
Synonyms and alternative names related to IL1R2
interleukin 1 receptor type 2 (IL1R2), interleukin 1 receptor, type II (Il1r2), interleukin 1 receptor type 2 (Il1r2), interleukin-like (KK34), CD121b, CDw121b, IL-1R-2, IL-1R2, IL-1RT-2, IL-1RT2, Il1r-2, IL1R2c, IL1RBProtein level used designations for IL1R2
- CD121 antigen-like family member B
- IL-1 type II receptor
- IL-1R-beta
- antigen CDw121b
- interleukin 1 receptor type II variant 3
- interleukin-1 receptor beta
- interleukin-1 receptor type 2
- interleukin-1 receptor type II
- type II interleukin-1 receptor, beta
- IL-1 receptor beta chain
- IL-1R-2
- IL-1RT-2
- IL-1RT2
- soluble type II IL-1 receptor
- interleukin 1 receptor, type II
- IL-1 receptor 2
- interleukin 1 receptor, beta
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