IL18BP Products
(Interleukin 18 Binding Protein (IL18BP))
Categories
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Featured IL18BP Categories
IL18BP Antibodies
High quality antibodies with extensive validation data.
IL18BP ELISA Kits
Reliable ELISA kits for a wide range of species.
IL18BP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL18BP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7437905
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6142329
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (1)
- (1)
Cat. No.
ABIN752938
Quantity
100 μL
Datasheet
Datasheet
Recommended IL18BP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957071
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962912
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957070
Quantity
96 tests
Datasheet
Datasheet
Recommended IL18BP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7274976
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274973
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274977
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL18BP products
: "Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R." in: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 354-373, (2019) (PubMed).: "Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients." in: Scandinavian journal of immunology, Vol. 87, Issue 5, pp. e12658, (2018) (PubMed).
: "Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model." in: Frontiers in pharmacology, Vol. 8, pp. 48, (2017) (PubMed).
: "Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 141, (2017) (PubMed).
: "Interleukin-18 modulation in autism spectrum disorders." in: Journal of neuroinflammation, Vol. 13, pp. 2, (2016) (PubMed).
: "IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice." in: Acta physiologica (Oxford, England), Vol. 213, Issue 2, pp. 492-504, (2015) (PubMed).
: "Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction." in: Molecular biology reports, Vol. 39, Issue 1, pp. 185-91, (2011) (PubMed).
: "Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1414-21, (2008) (PubMed).
Synonyms and alternative names related to IL18BP
interleukin 18 binding protein (IL18BP), interleukin 18 binding protein (Il18bp), Igifbp, IL-18BP, IL18BP, IL18BPa, MC54LProtein level used designations for IL18BP
- interleukin 18 binding protein
- interferon gamma inducing factor binding protein
- interferon gamma-inducing factor-binding protein
- interleukin-18-binding protein
- IL-18BP
- MC51L-53L-54L homolog gene product
- tadekinig-alfa
- interleukin-18 binding protein
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