IL12A Products
(Interleukin 12 alpha (IL12A))
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This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].
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Featured IL12A Categories
IL12A Antibodies
High quality antibodies with extensive validation data.
IL12A ELISA Kits
Reliable ELISA kits for a wide range of species.
IL12A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL12A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7430651
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7430654
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7428245
Quantity
100 μL
Datasheet
Datasheet
Recommended IL12A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN6730876
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957001
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Horse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957003
Quantity
96 tests
Datasheet
Datasheet
Recommended IL12A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307676
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Dog
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7387514
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Horse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7387520
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL12A products
: "Regulatory T Cells and Their Derived Cytokine, Interleukin-35, Reduce Pain in Experimental Autoimmune Encephalomyelitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 39, Issue 12, pp. 2326-2346, (2019) (PubMed).: "4,4'-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner." in: Oncotarget, Vol. 7, Issue 27, pp. 40978-40991, (2018) (PubMed).
: "MiR674 inhibits the neuraminidase-stimulated immune response on dendritic cells via down-regulated Mbnl3." in: Oncotarget, Vol. 7, Issue 31, pp. 48978-48994, (2018) (PubMed).
: "Lycium barbarum Polysaccharide Promotes Maturation of Dendritic Cell via Notch Signaling and Strengthens Dendritic Cell Mediated T Lymphocyte Cytotoxicity on Colon Cancer Cell CT26-WT." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 2305683, (2018) (PubMed).
: "The effect of human placental chorionic villi derived mesenchymal stem cell on triple-negative breast cancer hallmarks." in: PLoS ONE, Vol. 13, Issue 11, pp. e0207593, (2018) (PubMed).
: "Modulation of the Tumor Microenvironment by CXCR4 Antagonist-Armed Viral Oncotherapy Enhances the Antitumor Efficacy of Dendritic Cell Vaccines against Neuroblastoma in Syngeneic Mice." in: Viruses, Vol. 10, Issue 9, (2018) (PubMed).
: "Effect of IL-17 in the development of colon cancer in mice." in: Oncology letters, Vol. 12, Issue 6, pp. 4929-4936, (2017) (PubMed).
: "Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." in: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).
: "H9N2 Avian Influenza Virus Protein PB1 Enhances the Immune Responses of Bone Marrow-Derived Dendritic Cells by Down-Regulating miR375." in: Frontiers in microbiology, Vol. 8, pp. 287, (2017) (PubMed).
: "The immunosuppressive characteristics of FB1 by inhibition of maturation and function of BMDCs." in: International immunopharmacology, Vol. 47, pp. 206-211, (2017) (PubMed).
Synonyms and alternative names related to IL12A
interleukin 12A (IL12A), interleukin 12B (IL12B), interleukin 12b (Il12b), interleukin 12B (Il12b), interleukin 12a (Il12a), interleukin 12A (Il12a), Interleukin 12 level (IL12), interleukin 12a (il12a), CLMF, CLMF2, Il-12 p35, IL-12 p35, IL-12A, Il-12a, IL-12B, Il-12b, IL-12p35, Il-12p40, IL-12p40, Il12, IL12, IL12p35, Il12p40, IL12p40, Ll12a, NFSK, NKSF, NKSF1, NKSF2, P35, p35, p40Protein level used designations for IL12A
- CLMF p35
- IL-12 subunit p35
- IL-12, subunit p35
- IL35 subunit
- NF cell stimulatory factor chain 1
- NK cell stimulatory factor chain 1
- cytotoxic lymphocyte maturation factor 1, p35
- cytotoxic lymphocyte maturation factor 35 kDa subunit
- interleukin 12, p35
- interleukin-12 alpha chain
- interleukin-12 subunit alpha
- natural killer cell stimulatory factor 1, 35 kD subunit
- CLMF p40
- IL-12 subunit p40
- IL12, subunit p40
- NK cell stimulatory factor chain 2
- cytotoxic lymphocyte maturation factor 40 kDa subunit
- interleukin 12, p40
- interleukin-12 beta chain
- interleukin-12 subunit beta
- natural killer cell stimulatory factor, 40 kD subunit
- IL-12p35 subunit
- IL-12A
- interleukin 12
- IL-12 p40
- IL-23 subunit p40
- interleukin-12 p40
- IL-12B
- interleukin-12 p40 subunit
- interleukin 12B
- interleukin-12 p35 subunit
- IL-12 p40 subunit
- interleukin-12p40
- interleukin 12a p35 subunit
- interleukin 12 p35 subunit
- interleukin 12 35kDa subunit
- interleukin 12 polypeptide 35
- natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35
- IL-12 p35
- interleukin 12 40kDa subunit
- Cytotoxic lymphocyte maturation factor 35 kDa subunit
- interleukin 12 35kD subunit
- interleukin 12a
- interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
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