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IL12 Proteins

(Interleukin 12 (IL12))

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].

recommended

IL12 Protein (His-Avi Tag) (ABIN7274898)

IL12 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by SEC-HPLC

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recommended

IL12 Protein (AA 23-328) (His-Avi Tag,Biotin) (ABIN7274899)

IL12 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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recommended

IL12 Protein (AA 23-219, AA 23-328) (ABIN2018013)

IL12 Origin: Human Host: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active

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IL12 Proteins by Origin

Find IL12 Proteins for a variety of species such as anti-Human IL12, anti-Mouse IL12, anti-Rat IL12. The species listed below are among those available. Click on a link to go to the corresponding products.

IL12 Proteins by Source

Here you will find IL12 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IL12 Proteins by Protein Type

Here you can find IL12 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IL12 Proteins by Application

Find IL12 Proteins validated for a specific application such as BCA, SDS, FACS, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL12 Proteins by Biological Activity

Find IL12 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular IL12 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

IL12 Protein (His-Avi Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7274898

Quantity 100 μg

Datasheet Datasheet

IL12 Protein (AA 23-328) (His-Avi Tag,Biotin)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7274899

Quantity 100 μg

Datasheet Datasheet

IL12 Protein (AA 23-219, AA 23-328)

Reactivity Human

Source HEK-293T Cells

Validations

Cat. No. ABIN2018013

Quantity 1 mg

Datasheet Datasheet

IL12 Protein (AA 23-215) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7274908

Quantity 100 μg

Datasheet Datasheet

IL12 Protein (AA 23-328) (His tag,DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2181328

Quantity 50 μg

Datasheet Datasheet

IL12 Protein (AA 23-328) (His tag,AVI tag,DYKDDDDK Tag,Biotin)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN6973104

Quantity 200 μg

Datasheet Datasheet

IL12 Protein (AA 23-219) (Fc-His Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7491453

Quantity 100 μg

Datasheet Datasheet

IL12 Protein

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7455632

Quantity 50 μg

Datasheet Datasheet

IL12 Protein

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN7320573

Quantity 50 μg

Datasheet Datasheet

IL12 Protein (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317148

Quantity 50 μg

Datasheet Datasheet

IL12 Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6700019

Quantity 2 μg

Datasheet Datasheet

IL12 Protein

Reactivity Human

Source

Validations

Cat. No. ABIN1111712

Quantity 2 μg

Datasheet Datasheet

IL12 Protein (C-Term, Extracellular Domain)

Reactivity Human

Source HEK-293T Cells

Validations

Cat. No. ABIN1684636

Quantity 10 μg

Datasheet Datasheet

IL12 Protein (AA 23-328)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7505595

Quantity 100 μg

Datasheet Datasheet

IL12 Protein (AA 1-219) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7505604

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our IL12 Proteins

Ling, Gately, Gubler, Stern, Lin, Hollfelder, Su, Pan, Hakimi: "Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 1, pp. 116-27, (1995) (PubMed).

DAndrea, Aste-Amezaga, Valiante, Ma, Kubin, Trinchieri: "Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1041-8, (1993) (PubMed).

Schoenhaut, Chua, Wolitzky, Quinn, Dwyer, McComas, Familletti, Gately, Gubler: "Cloning and expression of murine IL-12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 11, pp. 3433-40, (1992) (PubMed).

DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

Aliases for IL12 Proteins

interleukin 12B (IL12B) Proteins
interleukin 12A (IL12A) Proteins
interleukin 12b (Il12b) Proteins
interleukin 12B (Il12b) Proteins
interleukin 12a (Il12a) Proteins
interleukin 12A (Il12a) Proteins
Interleukin 12 level (IL12) Proteins
interleukin 12a (il12a) Proteins
CLMF Proteins
CLMF2 Proteins
IL-12 Proteins
IL-12 p35 Proteins
Il-12a Proteins
IL-12B Proteins
Il-12b Proteins
IL-12p35 Proteins
Il-12p40 Proteins
IL-12p40 Proteins
Il12 Proteins
IL12B Proteins
Il12p40 Proteins
IL12p40 Proteins
Ll12a Proteins
LOC100217488 Proteins
NKSF Proteins
NKSF2 Proteins
p35 Proteins
p40 Proteins

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IL12 Proteins by Origin

IL12 Proteins by Source

IL12 Proteins by Protein Type

IL12 Proteins by Application

IL12 Proteins by Biological Activity

Popular IL12 Proteins

Latest Publications for our IL12 Proteins

Aliases for IL12 Proteins

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