IL-15 Products
(Interleukin 15 (IL15))
Categories
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011].
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Featured IL-15 Categories
IL-15 Antibodies
High quality antibodies with extensive validation data.
IL-15 ELISA Kits
Reliable ELISA kits for a wide range of species.
IL-15 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL-15 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7430678
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN517140
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7430681
Quantity
100 μL
Datasheet
Datasheet
Recommended IL-15 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957032
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957033
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957034
Quantity
96 tests
Datasheet
Datasheet
Recommended IL-15 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (5)
Cat. No.
ABIN7274953
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (3)
Cat. No.
ABIN6239761
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123549
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IL-15 products
: "Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion." in: Cell death & disease, Vol. 11, Issue 6, pp. 453, (2020) (PubMed).: "Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 255, pp. 81-93, (2018) (PubMed).
: "Combined effect of aerobic interval training and selenium nanoparticles on expression of IL-15 and IL-10/TNF-α ratio in skeletal muscle of 4T1 breast cancer mice with cachexia." in: Cytokine, Vol. 90, pp. 100-108, (2018) (PubMed).
: "Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes." in: Peptides, Vol. 99, pp. 14-19, (2018) (PubMed).
: "Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22." in: Cytokine, Vol. 108, pp. 182-189, (2018) (PubMed).
: ""Inflamm-aging" influences immune cell survival factors in human bone marrow." in: European journal of immunology, Vol. 47, Issue 3, pp. 481-492, (2017) (PubMed).
: "Dendritic Cell-Derived IL-32α: A Novel Inhibitory Cytokine of NK Cell Function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1290-1300, (2017) (PubMed).
: "A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions." in: Mayo Clinic proceedings, Vol. 91, Issue 6, pp. 812-9, (2016) (PubMed).
: "miR-15b is Downregulated in Myasthenia Gravis Patients and Directly Regulates the Expression of Interleukin-15 (IL-15) in Experimental Myasthenia Gravis Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1774-80, (2015) (PubMed).
: "A pancreatic tumor-specific biomarker characterized in humans and mice as an immunogenic onco-glycoprotein is efficient in dendritic cell vaccination." in: Oncotarget, Vol. 6, Issue 27, pp. 23462-79, (2015) (PubMed).
Synonyms and alternative names related to IL-15
interleukin 15 (IL15), interleukin 15 (Il15), AI503618, IL-15, IL15Protein level used designations for IL-15
- interleukin 15
- interleukin-15
- IL-15
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