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IL-11 Products

(Interleukin 11 (IL11))
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012].

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Featured IL-11 Categories

IL-11 Antibodies

High quality antibodies with extensive validation data.

IL-11 ELISA Kits

Reliable ELISA kits for a wide range of species.

IL-11 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL-11 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7430636
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN735023
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN6242412
Quantity 200 μL
Datasheet Datasheet

Recommended IL-11 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975352
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956991
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956992
Quantity 96 tests
Datasheet Datasheet

Recommended IL-11 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274885
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274875
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN6239760
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IL-11 products

Tu, Yang, Zhang, Lu, Ke, Tong, Kasimu, Hu, Xu, Li: "Regulatory effect of chemerin and therapeutic efficacy of chemerin‑9 in pancreatogenic diabetes mellitus." in: Molecular medicine reports, Vol. 21, Issue 3, pp. 981-988, (2020) (PubMed).

Chen, Chen, Xie, Huang, Dong, Han, Zhang, Zhou, Li, Huang, Lin: "DANCR Promotes Metastasis and Proliferation in Bladder Cancer Cells by Enhancing IL-11-STAT3 Signaling and CCND1 Expression." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 2, pp. 326-341, (2019) (PubMed).

Zhao, Liu, Liu, Qi, Hou, Chang, Ren: "Upregulation of IL-11, an IL-6 Family Cytokine, Promotes Tumor Progression and Correlates with Poor Prognosis in Non-Small Cell Lung Cancer." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 6, pp. 2213-2224, (2018) (PubMed).

Sano, Takei, Ueda, Tsumoto: "Production and characterization of genetically modified human IL-11 variants." in: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 2, pp. 205-217, (2017) (PubMed).

Prasad, Suchetha, Lakshmi, Darshan, Apoorva, Ashit: "Interleukin-11 - its role in the vicious cycle of inflammation, periodontitis and diabetes: A clinicobiochemical cross-sectional study." in: Journal of Indian Society of Periodontology, Vol. 19, Issue 2, pp. 159-63, (2015) (PubMed).

Pan, Xu, Liu, Zhang, Liu, Liu, Fu, Xu: "High expression of interleukin-11 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma." in: Cancer science, Vol. 106, Issue 5, pp. 592-7, (2015) (PubMed).

Zhang, Tao, Chopra, Dujmovic-Basuroski, Jin, Tang, Drulovic, Markovic-Plese: "IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5139-49, (2015) (PubMed).

Zhou, Ji, Cai, Shi, Chen, Yu, Zhu, Zhang: "MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11." in: BMC cancer, Vol. 15, pp. 343, (2015) (PubMed).

Marusyk, Tabassum, Altrock, Almendro, Michor, Polyak: "Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity." in: Nature, Vol. 514, Issue 7520, pp. 54-8, (2014) (PubMed).

Ren, Chen, Han, Fu, Chen: "Plasma interleukin-11 (IL-11) levels have diagnostic and prognostic roles in patients with pancreatic cancer." in: Tumour biology, Vol. 35, Issue 11, pp. 11467-72, (2014) (PubMed).

Synonyms and alternative names related to IL-11

interleukin 11 (IL11), interleukin 11 (Il11), AGIF, IL-11, Il-11, IL11

Protein level used designations for IL-11

  • interleukin 11
  • adipogenesis inhibitory factor
  • interleukin-11
  • oprelvekin
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