IL-10 Products
(Interleukin 10 (IL10))
Categories
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].
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Featured IL-10 Categories
IL-10 Antibodies
High quality antibodies with extensive validation data.
IL-10 ELISA Kits
Reliable ELISA kits for a wide range of species.
IL-10 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL-10 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7442330
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (10)
- (4)
Cat. No.
ABIN672051
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3023112
Quantity
100 μL
Datasheet
Datasheet
Recommended IL-10 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (18)
- (5)
Cat. No.
ABIN6574130
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (16)
- (5)
Cat. No.
ABIN6574129
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (26)
- (1)
Cat. No.
ABIN6963588
Quantity
96 tests
Datasheet
Datasheet
Recommended IL-10 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7274884
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
CHO Cells
Validations
- (3)
Cat. No.
ABIN2018051
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274896
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL-10 products
: "Suppression of Fpr2 expression protects against endotoxin-induced acute lung injury by interacting with Nrf2-regulated TAK1 activation." in: Biomedicine & pharmacotherapy, Vol. 125, pp. 109943, (2021) (PubMed).: "Major Depression in Children with Transfusion-Dependent Thalassemia Is Strongly Associated with the Combined Effects of Blood Transfusion Rate, Iron Overload, and Increased Pro-inflammatory Cytokines." in: Neurotoxicity research, Vol. 38, Issue 1, pp. 228-241, (2021) (PubMed).
: "Modulation of Gut Microbiota by Fucoxanthin During Alleviation of Obesity in High-Fat Diet-Fed Mice." in: Journal of agricultural and food chemistry, Vol. 68, Issue 18, pp. 5118-5128, (2021) (PubMed).
: "Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway." in: International immunopharmacology, Vol. 81, pp. 106287, (2021) (PubMed).
: "Exosomes derived from synovial fibroblasts under hypoxia aggravate rheumatoid arthritis by regulating Treg/Th17 balance." in: Experimental biology and medicine (Maywood, N.J.), Vol. 245, Issue 14, pp. 1177-1186, (2021) (PubMed).
: "Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats." in: Toxicology, Vol. 442, pp. 152556, (2021) (PubMed).
: "Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult." in: Frontiers in immunology, Vol. 12, pp. 649285, (2021) (PubMed).
: "Bafilomycin A1 Accelerates Chronic Refractory Wound Healing in db/db Mice." in: BioMed research international, Vol. 2020, pp. 6265701, (2021) (PubMed).
: "Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-α treatment." in: Journal of hepatology, Vol. 73, Issue 3, pp. 582-592, (2020) (PubMed).
: "Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signaling." in: Experimental biology and medicine (Maywood, N.J.), Vol. 244, Issue 3, pp. 213-226, (2020) (PubMed).
Synonyms and alternative names related to IL-10
interleukin 10 (IL10), interleukin 10 (Il10), CSIF, GVHDS, IL-10, Il-10, IL10A, IL10X, TGIFProtein level used designations for IL-10
- T-cell growth inhibitory factor
- cytokine synthesis inhibitory factor
- interleukin-10
- CSIF
- IL-10
- uncharacterized protein LOC100715618
- Cytokine synthesis inhibitory factor
- Interleukin-10
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