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IKZF1 Proteins

(IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2011].

recommended

IKZF1 Protein (AA 1-519) (His tag) (ABIN7123400)

IKZF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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recommended

IKZF1 Protein (AA 1-477) (GST tag) (ABIN1307650)

IKZF1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

IKZF1 Protein (AA 1-519) (Strep Tag) (ABIN3093023)

IKZF1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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IKZF1 Proteins by Origin

Find IKZF1 Proteins for a variety of species such as anti-Human IKZF1, anti-Mouse IKZF1. The species listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 Proteins by Source

Here you will find IKZF1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IKZF1 Proteins by Protein Type

Here you can find IKZF1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IKZF1 Proteins by Application

Find IKZF1 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular IKZF1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

IKZF1 Protein (AA 1-519) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123400

Quantity 50 μg

Datasheet Datasheet

IKZF1 Protein (AA 1-477) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1307650

Quantity 10 μg

Datasheet Datasheet

IKZF1 Protein (AA 1-519) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3093023

Quantity 1 mg

Datasheet Datasheet

IKZF1 Protein (AA 1-517) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3134815

Quantity 1 mg

Datasheet Datasheet

IKZF1 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2723364

Quantity 20 μg

Datasheet Datasheet

Aliases for IKZF1 Proteins

IKAROS family zinc finger 1 (IKZF1) Proteins
IKAROS family zinc finger 1 (Ikzf1) Proteins
IKAROS family zinc finger 1 (Ikaros) (ikzf1) Proteins
IKAROS family zinc finger 1 (ikzf1) Proteins
5832432G11Rik Proteins
hIk-1 Proteins
hik-1 Proteins
hlk-1 Proteins
Hs.54452 Proteins
hs.54452 Proteins
IK1 Proteins
ik1 Proteins
IKAROS Proteins
ikaros Proteins
Ikaros Proteins
ikzf1 Proteins
LyF-1 Proteins
LYF1 Proteins
lyf1 Proteins
MGC108252 Proteins
mKIAA4227 Proteins
PRO0758 Proteins
pro0758 Proteins
RGD1562979 Proteins
Zfpn1a1 Proteins
ZNFN1A1 Proteins
znfn1a1 Proteins
Znfn1a1 Proteins

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IKZF1 Proteins by Origin

IKZF1 Proteins by Source

IKZF1 Proteins by Protein Type

IKZF1 Proteins by Application

Popular IKZF1 Proteins

Aliases for IKZF1 Proteins

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