IKKi/IKKe Products
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
Categories
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].
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Featured IKKi/IKKe Categories
IKKi/IKKe Antibodies
High quality antibodies with extensive validation data.
IKKi/IKKe ELISA Kits
Reliable ELISA kits for a wide range of species.
IKKi/IKKe Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IKKi/IKKe Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (2)
- (4)
Cat. No.
ABIN3020771
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN6262509
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN392751
Quantity
400 μL
Datasheet
Datasheet
Recommended IKKi/IKKe ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967599
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951456
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1138007
Quantity
96 tests
Datasheet
Datasheet
Recommended IKKi/IKKe Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307642
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508967
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093125
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our IKKi/IKKe products
: "Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication." in: mBio, Vol. 10, Issue 4, (2020) (PubMed).: "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006347, (2017) (PubMed).
: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).
: "The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response." in: PLoS pathogens, Vol. 12, Issue 9, pp. e1005880, (2016) (PubMed).
: "Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response." in: Immunity, Vol. 40, Issue 6, pp. 880-95, (2014) (PubMed).
: "TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 1, pp. 90-102, (2013) (PubMed).
: "Integrative genomic approaches identify IKBKE as a breast cancer oncogene. ..." in: Cell, Vol. 129, Issue 6, pp. 1065-79, (2007) (PubMed).
: "Tubal flushing for subfertility." in: Cochrane database of systematic reviews (Online), Issue 3, pp. CD003718, (2007) (PubMed).
: "Antiviral gene expression in rheumatoid arthritis: role of IKKepsilon and interferon regulatory factor 3." in: Arthritis and rheumatism, Vol. 56, Issue 3, pp. 743-52, (2007) (PubMed).
: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).
Synonyms and alternative names related to IKKi/IKKe
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (ikbke), inhibitor of nuclear factor kappa B kinase subunit epsilon (IKBKE), inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog (ikbke.L), inhibitor of nuclear factor kappa B kinase subunit epsilon (ikbke), inhibitor of nuclear factor kappa B kinase subunit epsilon (Ikbke), inhibitor of kappaB kinase epsilon (Ikbke), AW558201, IKBKE, IKK-E, IKK-i, IKKE, IKKepsilon, IKKI, Ikki, MGC130907, zgc:100844Protein level used designations for IKKi/IKKe
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
- IKKe
- inhibitor of nuclear factor kappa-B kinase subunit epsilon
- inhibitor of nuclear factor kappa-B kinase subunit epsilon-like
- I-kappa-B kinase epsilon
- IKK-epsilon
- IKK-related kinase epsilon
- inducible I kappa-B kinase
- inducible IkappaB kinase
- inhibitor of kappaB kinase epsilon
- IKK-E
- inducible IKappaB kinase
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