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IKBKB Products

(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

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The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011].

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Featured IKBKB Categories

IKBKB Antibodies

High quality antibodies with extensive validation data.

IKBKB ELISA Kits

Reliable ELISA kits for a wide range of species.

IKBKB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IKBKB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
  • (10)
Cat. No. ABIN3022876
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application ELISA, WB, IHC, IF, ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN6256667
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN2856162
Quantity 100 μL
Datasheet Datasheet

Recommended IKBKB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967598
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967597
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956743
Quantity 96 tests
Datasheet Datasheet

Recommended IKBKB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307638
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123430
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307640
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IKBKB products

Wang, Chen, Fan, Li, Qu, Dong, Wang, Ji, Li: "Inhibition of DNM1L and mitochondrial fission attenuates inflammatory response in fibroblast-like synoviocytes of rheumatoid arthritis." in: Journal of cellular and molecular medicine, Vol. 24, Issue 2, pp. 1516-1528, (2021) (PubMed).

Mei, He, Zhang, Miao, Wen, Liu, Xu, Ye, Ye, Huang, Lin, Zhou, Zhao, Chen, Zhou, Li, Li: "Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p." in: Scientific reports, Vol. 9, Issue 1, pp. 19370, (2020) (PubMed).

Cleary, Mansoor, Settelmeyer, Ijiri, Ladner, Svalina, Rubin, Guttridge, Keller: "NFκB signaling in alveolar rhabdomyosarcoma." in: Disease models & mechanisms, Vol. 10, Issue 9, pp. 1109-1115, (2018) (PubMed).

Zong, Li, Liang, Dai, Zhang, Yan, Liu, Xu, Qian: "Nuclear Localization Leucine-Rich-Repeat Protein 1 Deficiency Protects Against Cardiac Hypertrophy by Pressure Overload." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 48, Issue 1, pp. 75-86, (2018) (PubMed).

Abdi, Lai, Paez-Gonzalez, Lay, Pyun, Kuo: "Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus." in: Nature communications, Vol. 9, Issue 1, pp. 1655, (2018) (PubMed).

De, Karim, Kiessu, Cushing, Lin, Ghandil, Hoarau, Casanova, Puel, Rao: "Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling." in: The Journal of biological chemistry, Vol. 293, Issue 39, pp. 15208-15220, (2018) (PubMed).

Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).

Wang, Liu, Wang, Wang, Tang, Jiang: "Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1282-1294, (2018) (PubMed).

Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

Liu, Ibi, Taniguchi, Lee, Herrema, Akosman, Mucka, Salazar Hernandez, Uyar, Park, Karin, Ozcan: "Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction." in: Cell, Vol. 167, Issue 4, pp. 1052-1066.e18, (2016) (PubMed).

Synonyms and alternative names related to IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog (ikbkb.L), inhibitor of nuclear factor kappa B kinase subunit beta (IKBKB), inhibitor of nuclear factor kappa B kinase subunit beta (ikbkb), I-kappaB kinase beta (IKKbeta), inhibitor of nuclear factor kappa B kinase subunit beta (Ikbkb), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), inhibitor of kappaB kinase beta (Ikbkb), AI132552, AIM-1, anon-89Bd, CG4201, DIK, dIKK, dIKK-beta, dIKKbeta, DLAK, dLak, Dmel\\CG4201, DmIKK, DmIKKb, Dmikkb, DmIKKBeta, DmIKKbeta, DmIkkbeta, Dmikkbeta, dmIKKbeta, IK, Ik, IKBKB, IKK, ikk, IKK-2, ikk-beta, IKK-beta, ikk2, IKK2, ikkb, IKKB, IKKb, Ikkb, ikkbeta, IKKbeta, Ikkbeta, IKK[b], ird, IRD-5, Ird-5, IRD5, Ird5, ird5/DmIkk[beta], Lak, LRK, NFKBIKB

Protein level used designations for IKBKB

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • inhibitor of nuclear factor kappa-B kinase subunit beta
  • inhibitor of nuclear factor kappa-B kinase subunit beta-like
  • CG4201-PB
  • IKK-like protein
  • LPS-responsive kinase
  • LPS-responsive-kinase
  • cactus kinase
  • deficient 5
  • immune response
  • ird5-PB
  • lipopolysaccharide activated kinase
  • mmune response deficient 5
  • I-kappa-B kinase 2
  • I-kappa-B-kinase beta
  • IKK-B
  • nuclear factor NF-kappa-B inhibitor kinase beta
  • IKK-beta
  • NFKBIKB
  • inhibitor of kappaB kinase beta
  • inhibitor of nuclear factor kappa B kinase beta subunit
  • inhibitor of kappa light chain gene enhancer in B cells, kinase beta
  • IKK2
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