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IKAP/p150 Products

(Elongator Complex Protein 1 (ELP1))

Categories

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq, Jul 2008].

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Featured IKAP/p150 Categories

IKAP/p150 Antibodies

High quality antibodies with extensive validation data.

IKAP/p150 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IKAP/p150 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC, IF
Validations
  • (5)
Cat. No. ABIN7151572
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN563666
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6142278
Quantity 100 μL
Datasheet Datasheet

Recommended IKAP/p150 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307636
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135967
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092293
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IKAP/p150 products

Lefler, Cohen, Kantor, Cheishvili, Even, Birger, Turetsky, Gil, Even-Ram, Aizenman, Bashir, Maayan, Razin, Reubinoff, Weil: "Familial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP Downregulation." in: PLoS ONE, Vol. 10, Issue 10, pp. e0138807, (2015) (PubMed).

Hawkes, Otero, Winkler, Marshall, Dahmus, Krappmann, Scheidereit, Thomas, Schiavo, Erdjument-Bromage, Tempst, Svejstrup: "Purification and characterization of the human elongator complex." in: The Journal of biological chemistry, Vol. 277, Issue 4, pp. 3047-52, (2002) (PubMed).

Anderson, Coli, Daly, Kichula, Rork, Volpi, Ekstein, Rubin: "Familial dysautonomia is caused by mutations of the IKAP gene." in: American journal of human genetics, Vol. 68, Issue 3, pp. 753-8, (2001) (PubMed).

Krappmann, Hatada, Tegethoff, Li, Klippel, Giese, Baeuerle, Scheidereit: "The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component." in: The Journal of biological chemistry, Vol. 275, Issue 38, pp. 29779-87, (2000) (PubMed).

Cohen, Henzel, Baeuerle: "IKAP is a scaffold protein of the IkappaB kinase complex." in: Nature, Vol. 395, Issue 6699, pp. 292-6, (1998) (PubMed).

Synonyms and alternative names related to IKAP/p150

elongator complex protein 1 (ELP1), elongator complex protein 1 (Elp1), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), ielongator complex protein 1 S homeolog (elp1.S), elongator complex protein 1 (elp1), inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein (Ikbkap), 3110040G09Rik, 6030413P05, C78473, DKFZp469N1415, DYS, ELP1, Elp1, FD, IKAP, IKBKAP, Ikbkap, IKI3, TOT1

Protein level used designations for IKAP/p150

  • IKK complex-associated protein
  • elongator acetyltransferase complex subunit 1
  • elongator complex protein 1
  • ikappaB kinase complex-associated protein
  • p150
  • ELP1
  • inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • putative elongator complex protein 1
  • IKK-complex-associated protein IKAP
  • IKAP
  • Elongator complex protein 1-like protein
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