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IGFBP7 Products

(Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011].

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Featured IGFBP7 Categories

IGFBP7 Antibodies

High quality antibodies with extensive validation data.

IGFBP7 ELISA Kits

Reliable ELISA kits for a wide range of species.

IGFBP7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IGFBP7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7439126
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN1724903
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7433918
Quantity 100 μL
Datasheet Datasheet

Recommended IGFBP7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956830
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967676
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956831
Quantity 96 tests
Datasheet Datasheet

Recommended IGFBP7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7092833
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274865
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123465
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IGFBP7 products

Thomas, Zondler, Ludwig, Kardell, Lüneburg, Henke, Mersmann, Margraf, Spieker, Tekath, Velic, Holtmeier, Hermann, Jankowski, Meersch, Vestweber, Westphal, Roth, Schäfers, Kellum, Lowell, Rossaint et al.: "Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells. ..." in: JCI insight, Vol. 7, Issue 21, (2022) (PubMed).

Yagi, Nishigori, Murakami, Osaki, Muto, Iba, Minatoya, Ikeda, Ishibashi-Ueda, Morisaki, Ogino, Tanaka, Sasaki, Matsuda, Minamino: "Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progression." in: Scientific reports, Vol. 10, Issue 1, pp. 6429, (2020) (PubMed).

Wu, Chang, Tsai, Liu, Hsu, Chang, Yu, Shih: "IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer." in: Cancers, Vol. 11, Issue 1, (2019) (PubMed).

Lisowska, Święcki, Knapp, Gil, Musiał, Kamiński, Hirnle, Tycińska: "Insulin-like growth factor-binding protein 7 (IGFBP 7) as a new biomarker in coronary heart disease." in: Advances in medical sciences, Vol. 64, Issue 1, pp. 195-201, (2019) (PubMed).

Watanabe, Takiyama, Honjyo, Makino, Fujita, Tateno, Haneda: "Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells." in: PLoS ONE, Vol. 11, Issue 3, pp. e0150897, (2016) (PubMed).

Nakamura, Hosoyama, Kawamura, Takeuchi, Tanaka, Samura, Ueno, Nishimoto, Kurazumi, Suzuki, Ito, Sakata, Mikamo, Li, Hamano: "Influence of aging on the quantity and quality of human cardiac stem cells." in: Scientific reports, Vol. 6, pp. 22781, (2016) (PubMed).

Benassi, Pazzaglia, Novello, Quattrini, Pollino, Magagnoli, Picci, Conti: "Tissue and serum IGFBP7 protein as biomarker in high-grade soft tissue sarcoma." in: American journal of cancer research, Vol. 5, Issue 11, pp. 3446-54, (2016) (PubMed).

Gambaro, Quinn, Cáceres-Gorriti, Shapiro, Provencher, Rahimi, Mes-Masson, Tonin: "Low levels of IGFBP7 expression in high-grade serous ovarian carcinoma is associated with patient outcome." in: BMC cancer, Vol. 15, pp. 135, (2015) (PubMed).

Calon, Lonardo, Berenguer-Llergo, Espinet, Hernando-Momblona, Iglesias, Sevillano, Palomo-Ponce, Tauriello, Byrom, Cortina, Morral, Barceló, Tosi, Riera, Attolini, Rossell, Sancho, Batlle: "Stromal gene expression defines poor-prognosis subtypes in colorectal cancer." in: Nature genetics, Vol. 47, Issue 4, pp. 320-9, (2015) (PubMed).

Verhagen, de Leeuw, Roemer, Denkers, Pouwels, Rutten, Celie, Ossenkoppele, Schuurhuis, Smit: "IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival." in: Cell death & disease, Vol. 5, pp. e1300, (2014) (PubMed).

Synonyms and alternative names related to IGFBP7

insulin like growth factor binding protein 7 (IGFBP7), insulin-like growth factor binding protein 7 (igfbp7), insulin-like growth factor binding protein 7 (Igfbp7), insulin like growth factor binding protein 7 (Igfbp7), AGM, FSTL2, Fstl2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, Mac25, PSF, RAMSVPS, TAF, zgc:85888

Protein level used designations for IGFBP7

  • insulin-like growth factor-binding protein 7
  • agm
  • angiomodulin
  • IGF-binding protein 7
  • IGFBP-rP1
  • PGI2-stimulating factor
  • prostacyclin-stimulating factor
  • tumor-derived adhesion factor
  • IBP-7
  • IGFBP-7
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