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IGF2R Products

(Insulin-Like Growth Factor 2 Receptor (IGF2R))
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013].

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Featured IGF2R Categories

IGF2R Antibodies

High quality antibodies with extensive validation data.

IGF2R ELISA Kits

Reliable ELISA kits for a wide range of species.

IGF2R Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IGF2R Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Non-Human Primate
Application WB, FACS, IP
Validations
  • (2)
  • (4)
Cat. No. ABIN94039
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7267905
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN5693085
Quantity 100 μg
Datasheet Datasheet

Recommended IGF2R ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967650
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956801
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2859333
Quantity 96 tests
Datasheet Datasheet

Recommended IGF2R Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123457
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307559
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (1)
Cat. No. ABIN1046788
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IGF2R products

Gerber, Mosser, Boury-Jamot, Stumpe, Piersigilli, Goepfert, Dengjel, Albrecht, Magara, Fraering: "The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease." in: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 13, (2019) (PubMed).

Godoy-Parejo, Deng, Liu, Chen: "Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells." in: Stem cells (Dayton, Ohio), Vol. 37, Issue 8, pp. 1030-1041, (2019) (PubMed).

Kakegawa, Katoh, Narumi, Miura, Motohashi, Takahashi, Kohda, Fukazawa, Yuzaki, Matsuda: "Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning." in: Neuron, Vol. 99, Issue 5, pp. 985-998.e6, (2018) (PubMed).

Mu, Zhang, Wang, Xu, Ahmed, Pang, Chibbar, Freywald, Huang, Zhu, Xiang: "Enhanced suppression of polyclonal CD8+25+regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes." in: Journal of leukocyte biology, Vol. 101, Issue 5, pp. 1221-1231, (2017) (PubMed).

Ahmed, Xiang: "mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A." in: Cell discovery, Vol. 3, pp. 17011, (2017) (PubMed).

Liu, Yu, Wu, Sun, Su, You, Xin: "CD44+fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling." in: Journal of cellular and molecular medicine, Vol. 21, Issue 9, pp. 1979-1988, (2017) (PubMed).

Martín-Montañez, Millon, Boraldi, Garcia-Guirado, Pedraza, Lara, Santin, Pavia, Garcia-Fernandez: "IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids." in: Redox biology, Vol. 13, pp. 69-81, (2017) (PubMed).

Takahashi, Mashima, Miura, Maeda, Goto, Goto, Sun-Wada, Wada, Ohnishi: "Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models." in: Scientific reports, Vol. 7, Issue 1, pp. 2817, (2017) (PubMed).

Chanprasertyothin, Jongjaroenprasert, Ongphiphadhanakul: "The association of soluble IGF2R and IGF2R gene polymorphism with type 2 diabetes." in: Journal of diabetes research, Vol. 2015, pp. 216383, (2015) (PubMed).

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Synonyms and alternative names related to IGF2R

insulin like growth factor 2 receptor (IGF2R), insulin-like growth factor 2 receptor (Igf2r), insulin like growth factor 2 receptor (igf2r), AI661837, CD222, cd222, CI-MPR, CIMPR, cimpr, M6P-R, m6p-r, M6P/IGF2R, MPR1, Mpr300, MPRI, mpri

Protein level used designations for IGF2R

  • 300 kDa mannose 6-phosphate receptor
  • CI Man-6-P receptor
  • CI-MPR
  • IGF-II receptor
  • M6P/IGF2 receptor
  • M6P/IGF2R
  • M6PR
  • MPR 300
  • cation-independent mannose-6 phosphate receptor
  • cation-independent mannose-6-phosphate receptor
  • insulin-like growth factor II receptor
  • IGF-II/CI-MPR
  • cation-independent MPR
  • cation-independent mannose 6-phosphate receptor
  • mannose-6-phosphate receptor, cation independent
  • insulin-like growth factor receptor type 2
  • cation-independent mannose 6 phosphate receptor
  • insulin-like growth factor 2 receptor
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