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IFNGR2 Products

(Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))

Categories

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008].

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Featured IFNGR2 Categories

IFNGR2 Antibodies

High quality antibodies with extensive validation data.

IFNGR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

IFNGR2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFNGR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN652277
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7156602
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7239065
Quantity 200 μL
Datasheet Datasheet

Recommended IFNGR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967749
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730713
Quantity 96 tests
Datasheet Datasheet

Recommended IFNGR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964277
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307502
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307501
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our IFNGR2 products

Nagel, Pommerenke, Meyer, Kaufmann, MacLeod, Drexler: "Aberrant expression of NKL homeobox gene HLX in Hodgkin lymphoma." in: Oncotarget, Vol. 9, Issue 18, pp. 14338-14353, (2018) (PubMed).

Li, Chen, Zeng, He, Chen, Ma, Bi, Zhu, Guan: "CD133+ liver cancer stem cells resist interferon-gamma-induced autophagy." in: BMC cancer, Vol. 16, pp. 15, (2016) (PubMed).

Sullivan, Lewis, Hill, Pandey, Jackson, Cabral, Smith, Liggett, Gomez, Galbraith, DeGregori, Espinosa: "Trisomy 21 consistently activates the interferon response." in: eLife, Vol. 5, (2016) (PubMed).

Blouin, Hamon, Gonnord, Boularan, Kagan, Viaris de Lesegno, Ruez, Mailfert, Bertaux, Loew, Wunder, Johannes, Vogt, Contreras, Marguet, Casanova, Galès, He, Lamaze: "Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation." in: Cell, Vol. 166, Issue 4, pp. 920-934, (2016) (PubMed).

Tattermusch, Skinner, Chaussabel, Banchereau, Berry, McNab, OGarra, Taylor, Bangham: "Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy." in: PLoS pathogens, Vol. 8, Issue 1, pp. e1002480, (2012) (PubMed).

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Ivanidze, Hoffmann, Lochmüller, Engel, Hohlfeld, Dornmair: "Inclusion body myositis: laser microdissection reveals differential up-regulation of IFN-γ signaling cascade in attacked versus nonattacked myofibers." in: The American journal of pathology, Vol. 179, Issue 3, pp. 1347-59, (2011) (PubMed).

de Paus, Kilic, van Dissel, van de Vosse: "Effect of amino acid substitutions in the human IFN-γR2 on IFN-γ responsiveness." in: Genes and immunity, Vol. 12, Issue 2, pp. 136-44, (2011) (PubMed).

Hashioka, Klegeris, Schwab, Yu, McGeer: "Differential expression of interferon-gamma receptor on human glial cells in vivo and in vitro." in: Journal of neuroimmunology, Vol. 225, Issue 1-2, pp. 91-9, (2010) (PubMed).

Hashioka, Klegeris, Schwab, McGeer: "Interferon-gamma-dependent cytotoxic activation of human astrocytes and astrocytoma cells." in: Neurobiology of aging, Vol. 30, Issue 12, pp. 1924-35, (2009) (PubMed).

Synonyms and alternative names related to IFNGR2

interferon gamma receptor 2 (Ifngr2), interferon gamma receptor 2 (IFNGR2), interferon gamma receptor 2 (LOC487739), AF-1, Ifgr2, IFGR2, Ifgt, IFNGT1

Protein level used designations for IFNGR2

  • IFN-gamma receptor 2
  • IFN-gamma-R2
  • interferon gamma receptor 2
  • interferon gamma receptor accessory factor 1
  • interferon gamma receptor accessory factor-1
  • interferon gamma receptor beta chain
  • interferon gamma transducer 1
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