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IFNE Products

(Interferon epsilon (IFNE))

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Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

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Featured IFNE Categories

IFNE Antibodies

High quality antibodies with extensive validation data.

IFNE ELISA Kits

Reliable ELISA kits for a wide range of species.

IFNE Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFNE Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IP
Validations
  • (4)
Cat. No. ABIN567025
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN567024
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN949943
Quantity 100 μL
Datasheet Datasheet

Recommended IFNE ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967732
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974799
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1138426
Quantity 96 tests
Datasheet Datasheet

Recommended IFNE Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307496
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307494
Quantity 10 μg
Datasheet Datasheet
Reactivity Horse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421068
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IFNE products

Matsumiya, Prescott, Stafforini: "IFN-epsilon mediates TNF-alpha-induced STAT1 phosphorylation and induction of retinoic acid-inducible gene-I in human cervical cancer cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 7, pp. 4542-9, (2007) (PubMed).

Synonyms and alternative names related to IFNE

interferon epsilon (IFNE), interferon epsilon (Ifne), IFN-E, IFN-epsilon, Ifn-tau-1, IFNE1, Ifne1, IFNT1, Ifnt1, INFE1, Infe1, PRO655

Protein level used designations for IFNE

  • IFN-epsilon
  • interferon epsilon
  • interferon epsilon 1
  • interferon epsilon-1
  • interferon tau-1
  • interferon-epsilon
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