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IFNAR1 Products

(Interferon alpha/beta Receptor 1 (IFNAR1))

Categories

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq, Jul 2008].

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Featured IFNAR1 Categories

IFNAR1 Antibodies

High quality antibodies with extensive validation data.

IFNAR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

IFNAR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFNAR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (7)
Cat. No. ABIN7437731
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7267947
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN652490
Quantity 400 μL
Datasheet Datasheet

Recommended IFNAR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967723
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967724
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730350
Quantity 96 tests
Datasheet Datasheet

Recommended IFNAR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6964273
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7491022
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7490868
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IFNAR1 products

Jia, Thelwell, Dilger, Bird, Daniels, Wadhwa: "Endothelial cell functions impaired by interferon in vitro: Insights into the molecular mechanism of thrombotic microangiopathy associated with interferon therapy." in: Thrombosis research, Vol. 163, pp. 105-116, (2018) (PubMed).

Yu, Wan, Cao, Zhang, Chen, Tan, Wang, Sun, Zhang, Wan, Zhu, Liu, Wu, Liu, Wu: "Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action." in: Scientific reports, Vol. 7, Issue 1, pp. 1729, (2017) (PubMed).

Dendrou, Cortes, Shipman, Evans, Attfield, Jostins, Barber, Kaur, Kuttikkatte, Leach, Desel, Faergeman, Cheeseman, Neville, Sawcer, Compston, Johnson, Everett, Bell, Karpe, Ultsch, Eigenbrot, McVean et al.: "Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. ..." in: Science translational medicine, Vol. 8, Issue 363, pp. 363ra149, (2017) (PubMed).

Fuchs, Kaiser-Labusch, Bank, Ammann, Kolb-Kokocinski, Edelbusch, Omran, Ehl: "Tyrosine kinase 2 is not limiting human antiviral type III interferon responses." in: European journal of immunology, Vol. 46, Issue 11, pp. 2639-2649, (2016) (PubMed).

Ramachandran, Yu, Dyczynski, Baskaran, Zhang, Lulla, Lulla, Saul, Nelander, Dimberg, Merits, Leja-Jarblad, Essand: "Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2016) (PubMed).

Sullivan, Lewis, Hill, Pandey, Jackson, Cabral, Smith, Liggett, Gomez, Galbraith, DeGregori, Espinosa: "Trisomy 21 consistently activates the interferon response." in: eLife, Vol. 5, (2016) (PubMed).

Taylor, Minter, Newman, Zhang, Adlard, Crack: "Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease." in: Neurobiology of aging, Vol. 35, Issue 5, pp. 1012-23, (2014) (PubMed).

Minter, Zhang, Ates, Taylor, Crack: "Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells." in: Journal of neuroinflammation, Vol. 11, pp. 43, (2014) (PubMed).

Chort, Alves, Marinello, Dufresnois, Dornbierer, Tesson, Latouche, Baker, Barkats, El Hachimi, Ruberg, Janer, Stevanin, Brice, Sittler: "Interferon β induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice." in: Brain : a journal of neurology, Vol. 136, Issue Pt 6, pp. 1732-45, (2013) (PubMed).

Stone, Giugliano, Schnell, Cheng, Leahy, Golden-Mason, Gale, Rosen: "Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells." in: PLoS pathogens, Vol. 9, Issue 4, pp. e1003316, (2013) (PubMed).

Synonyms and alternative names related to IFNAR1

interferon alpha and beta receptor subunit 1 (IFNAR1), interferon-alpha/beta receptor alpha chain-like (ifnar1), interferon (alpha and beta) receptor 1 (Ifnar1), interferon alpha and beta receptor subunit 1 (Ifnar1), interferon alpha/beta receptor 1 (LOC609830), AVP, CD118, Ifar, IFN-alpha-REC, IFN-R-1, Ifnar, IFNAR, ifnar1, IFNAR1, IFNBR, Ifrc, IFRC, Infar

Protein level used designations for IFNAR1

  • interferon alpha/beta receptor 1
  • interferon receptor
  • soluble receptor
  • interferon-alpha receptor 1
  • putative interferon-alpha/beta receptor alpha chain
  • interferon receptor 1
  • interferon (alpha, beta and omega) receptor 1
  • interferon alpha/beta receptor 1-like
  • IFN-R-1
  • IFN-alpha/beta receptor 1
  • IFN-alpha/betaR
  • INF-a receptor
  • interferon-alpha/beta receptor 1
  • type I interferon receptor 1
  • CRF2-1
  • alpha-type antiviral protein
  • beta-type antiviral protein
  • cytokine receptor class-II member 1
  • cytokine receptor family 2 member 1
  • interferon-alpha/beta receptor alpha chain
  • interferon-beta receptor 1
  • interferon (alpha and beta) receptor 1
  • IFN-alpha-REC
  • interferon, alpha; receptor
  • Interferon-alpha/beta receptor alpha chain
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