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IFITM1 Products

(Interferon-Induced Transmembrane Protein 1 (IFITM1))

Categories

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53- dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

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Featured IFITM1 Categories

IFITM1 Antibodies

High quality antibodies with extensive validation data.

IFITM1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFITM1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN1680390
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN3187970
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7260992
Quantity 200 μL
Datasheet Datasheet

Recommended IFITM1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967764
Quantity 96 tests
Datasheet Datasheet

Recommended IFITM1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307435
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330218
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3112856
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IFITM1 products

Wu, Dao Thi, Huang, Billerbeck, Saha, Hoffmann, Wang, Silva, Sarbanes, Sun, Andrus, Yu, Quirk, Li, MacDonald, Schneider, An, Rosenberg, Rice: "Intrinsic Immunity Shapes Viral Resistance of Stem Cells." in: Cell, Vol. 172, Issue 3, pp. 423-438.e25, (2019) (PubMed).

Teng, Luo, Yu, Chen, Huang, Chen, Xie, Zeng, Luo, Xiong, Liu, Hou, Feng: "CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells." in: Genes and immunity, (2018) (PubMed).

Parra-Herran, Yuan, Nucci, Quade: "Targeted development of specific biomarkers of endometrial stromal cell differentiation using bioinformatics: the IFITM1 model." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 27, Issue 4, pp. 569-79, (2014) (PubMed).

Zhang, Zhang, Zan, Du, Yang, Tien: "Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins." in: The Journal of general virology, Vol. 96, Issue Pt 1, pp. 170-82, (2014) (PubMed).

Klymiuk, Kenner, Adler, Busch, Boersma, Irmler, Fridrich, Gailus-Durner, Fuchs, Leitner, Müller, Kühn, Schlederer, Treise, de Angelis, Beckers: "In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis." in: PLoS ONE, Vol. 7, Issue 10, pp. e44609, (2012) (PubMed).

Ma, Zhang, Fu, Xia, Zhan, Li, Wang, Wu: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).

Mosbruger, Duggal, Goedert, Kirk, Hoots, Tobler, Busch, Peters, Rosen, Thomas, Thio: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, (2010) (PubMed).

Xu, Yang, Hu: "Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation." in: Acta biochimica et biophysica Sinica, Vol. 41, Issue 6, pp. 488-94, (2009) (PubMed).

Yang, Chen, Lin, Yu, Liu, Wang, Liu, Chen et al.: "Nickel catalysts bearing bidentate alpha-aminoaldimines for ethylene polymerization--independent and cooperative structure/reactivity relationship resulting from unsymmetric square planar..." in: Dalton transactions (Cambridge, England : 2003), Issue 7, pp. 1243-50, (2009) (PubMed).

Yang, Xu, Chen, Hu: "IFITM1 plays an essential role in the antiproliferative action of interferon-gamma." in: Oncogene, Vol. 26, Issue 4, pp. 594-603, (2007) (PubMed).

Synonyms and alternative names related to IFITM1

interferon induced transmembrane protein 1 (Ifitm1), interferon induced transmembrane protein 1 (IFITM1), interferon induced transmembrane protein 1 (9-27) (IFITM1), 9-27, 1110036C17Rik, CD225, DSPA2a, IFI17, LEU13, Mil-2, Mil2

Protein level used designations for IFITM1

  • interferon-induced transmembrane protein 1
  • interferon induced transmembrane protein 1 (9-27)
  • interferon induced transmembrane protein 1
  • dispanin subfamily A member 2a
  • interferon-induced protein 17
  • interferon-inducible protein 9-27
  • leu-13 antigen
  • fragilis protein 2
  • fragilis2
  • ifitm-like protein 2
  • interferon induced transmembrane protein 2 like
  • interferon-induced membrane protein Leu-13/9-27
  • interferon-induced transmembrane protein 1 (9-27)
  • interferon-induced transmembrane protein 1 (9-27) isoform 1
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