IFIH1 Products
(Interferon Induced with Helicase C Domain 1 (IFIH1))
Categories
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents\; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012].
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Featured IFIH1 Categories
IFIH1 Antibodies
High quality antibodies with extensive validation data.
IFIH1 ELISA Kits
Reliable ELISA kits for a wide range of species.
IFIH1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IFIH1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6142174
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6258879
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6262453
Quantity
100 μL
Datasheet
Datasheet
Recommended IFIH1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967752
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956907
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229146
Quantity
96 tests
Datasheet
Datasheet
Recommended IFIH1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123492
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307422
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307420
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our IFIH1 products
: "DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy." in: BMC biology, Vol. 18, Issue 1, pp. 32, (2020) (PubMed).: "TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages." in: Experimental cell research, Vol. 345, Issue 1, pp. 70-81, (2016) (PubMed).
: "Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop." in: Scientific reports, Vol. 6, pp. 20158, (2016) (PubMed).
: "FUBP1: a new protagonist in splicing regulation of the DMD gene." in: Nucleic acids research, Vol. 43, Issue 4, pp. 2378-89, (2015) (PubMed).
: "A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128039, (2015) (PubMed).
: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).
: "Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions." in: Nature communications, Vol. 6, pp. 6669, (2015) (PubMed).
: "Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus." in: Journal of translational medicine, Vol. 12, Issue 1, pp. 303, (2014) (PubMed).
: "Anti-MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis." in: Journal of immunology research, Vol. 2014, pp. 290797, (2014) (PubMed).
: "Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study." in: Arthritis research & therapy, Vol. 16, Issue 4, pp. R138, (2014) (PubMed).
Synonyms and alternative names related to IFIH1
interferon induced with helicase C domain 1 (IFIH1), interferon induced with helicase C domain 1 (Ifih1), 9130009C22Rik, Helicard, Hlcd, IDDM19, MDA-5, MDA5, RGD1560496, RLR-2Protein level used designations for IFIH1
- interferon-induced helicase C domain-containing protein 1
- melanoma differentiation associated protein-5
- melanoma differentiation-associated protein 5
- CADM-140 autoantigen
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
- RIG-I-like receptor 2
- RNA helicase-DEAD box protein 116
- clinically amyopathic dermatomyositis autoantigen 140 kDa
- helicard
- helicase with 2 CARD domains
- murabutide down-regulated protein
- interferon induced with helicase C domain protein 1
- melanoma differentiation associated protein 5
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