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IER3 Products

(Immediate Early Response 3 (IER3))
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008].

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Featured IER3 Categories

IER3 Antibodies

High quality antibodies with extensive validation data.

IER3 ELISA Kits

Reliable ELISA kits for a wide range of species.

IER3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IER3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN655735
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p), EIA
Validations
  • (5)
Cat. No. ABIN952818
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6142158
Quantity 100 μL
Datasheet Datasheet

Recommended IER3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967570
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2948408
Quantity 96 tests
Datasheet Datasheet

Recommended IER3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123403
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307396
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1787844
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IER3 products

Ito, Ozaki, Chanasong, Mizutani, Oyama, Sakurai, Matsumoto, Takemura, Kawahara: "Activation of ERK/IER3/PP2A-B56γ-positive feedback loop in lung adenocarcinoma by allelic deletion of B56γ gene." in: Oncology reports, Vol. 35, Issue 5, pp. 2635-42, (2016) (PubMed).

Kawahara, Maenaka, Shimada, Nishimura, Sakurai: "Dynamic regulation of extracellular signal-regulated kinase (ERK) by protein phosphatase 2A regulatory subunit B56?1 in nuclei induces cell migration." in: PLoS ONE, Vol. 8, Issue 5, pp. e63729, (2013) (PubMed).

Chen, Huang, Nakatsu, Xue, Deng, Fan: "Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells." in: Human molecular genetics, Vol. 22, Issue 7, pp. 1271-9, (2013) (PubMed).

Akilov, Wu, Ustyugova, Falo, Geskin: "Resistance of Sézary cells to TNF-α-induced apoptosis is mediated in part by a loss of TNFR1 and a high level of the IER3 expression." in: Experimental dermatology, Vol. 21, Issue 4, pp. 287-92, (2012) (PubMed).

Feldmann, Pittelkow, Roche, Kumar, Grande: "Expression of an immediate early gene, IEX-1, in human tissues." in: Histochemistry and cell biology, Vol. 115, Issue 6, pp. 489-97, (2001) (PubMed).

Arlt, Grobe, Sieke, Kruse, Fölsch, Schmidt, Schäfer: "Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells." in: Oncogene, Vol. 20, Issue 1, pp. 69-76, (2001) (PubMed).

Wu, Ao, Prasad, Wu, Schlossman: "IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival." in: Science (New York, N.Y.), Vol. 281, Issue 5379, pp. 998-1001, (1998) (PubMed).

Kondratyev, Chung, Jung: "Identification and characterization of a radiation-inducible glycosylated human early-response gene." in: Cancer research, Vol. 56, Issue 7, pp. 1498-502, (1996) (PubMed).

Synonyms and alternative names related to IER3

immediate early response 3 (IER3), immediate early response 3 (Ier3), AI663993, cI-3, DIF-2, DIF2, Dif2, GLY96, gly96, IER3, IEX-1, IEX-1L, IEX1, Iex1, Ler3, PRG1, Prg1

Protein level used designations for IER3

  • PACAP-responsive gene 1 protein
  • anti-death protein
  • differentiation-dependent gene 2 protein
  • expressed in pancreatic carcinoma
  • gly96, mouse, homolog of
  • immediate early protein GLY96
  • immediate early response 3 protein
  • immediately early gene X-1
  • protein DIF-2
  • radiation-inducible immediate-early gene IEX-1
  • cAMP inducible gene 3
  • immediate early response 3
  • ATP-binding cassette, sub-family F (GCN20), member 1
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