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IDS Products

(Iduronate 2-Sulfatase (IDS))

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Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2009].

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Featured IDS Categories

IDS Antibodies

High quality antibodies with extensive validation data.

IDS ELISA Kits

Reliable ELISA kits for a wide range of species.

IDS Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IDS Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7436576
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p), IF, FACS
Validations
  • (13)
Cat. No. ABIN1498797
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p), IF, FACS
Validations
  • (14)
Cat. No. ABIN1498798
Quantity 100 μL
Datasheet Datasheet

Recommended IDS ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956651
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975413
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN3044712
Quantity 96 tests
Datasheet Datasheet

Recommended IDS Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307391
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307390
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399523
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IDS products

Bellesso, Salvalaio, Lualdi, Tognon, Costa, Braghetta, Giraudo, Stramare, Rigon, Filocamo, Tomanin, Moro: "FGF signaling deregulation is associated with early developmental skeletal defects in animal models for mucopolysaccharidosis type II (MPSII)." in: Human molecular genetics, Vol. 27, Issue 13, pp. 2262-2275, (2019) (PubMed).

Keeratichamroen, Cairns, Wattanasirichaigoon, Wasant, Ngiwsara, Suwannarat, Pangkanon, Kuptanon, Tanpaiboon, Rujirawat, Liammongkolkul, Svasti: "Molecular analysis of the iduronate-2-sulfatase gene in Thai patients with Hunter syndrome." in: Journal of inherited metabolic disease, Vol. 31 Suppl 2, pp. S303-11, (2011) (PubMed).

Synonyms and alternative names related to IDS

iduronate 2-sulfatase (IDS), iduronate 2-sulfatase (CpipJ_CPIJ004938), iduronate 2-sulfatase (ids), iduronate 2-sulfatase (Ids), AW214631, mps2, MPS2, sids, SIDS, zgc:158245

Protein level used designations for IDS

  • iduronate 2-sulfatase (Hunter syndrome)
  • iduronate-2-sulfatase
  • iduronate 2-sulfatase
  • iduronate 2-sulfatase-like
  • alpha-L-iduronate sulfate sulfatase
  • iduronate 2-sulfatase 14 kDa chain
  • iduronate 2-sulfatase 42 kDa chain
  • idursulfase
  • iduronate sulfatase
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