IDO1 Products
(Indoleamine 2,3-Dioxygenase 1 (IDO1))
Categories
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].
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Featured IDO1 Categories
IDO1 Antibodies
High quality antibodies with extensive validation data.
IDO1 ELISA Kits
Reliable ELISA kits for a wide range of species.
IDO1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IDO1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
- (4)
Cat. No.
ABIN185488
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN1043819
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN517166
Quantity
100 μg
Datasheet
Datasheet
Recommended IDO1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975449
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6974104
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967580
Quantity
96 tests
Datasheet
Datasheet
Recommended IDO1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123419
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307387
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7320560
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IDO1 products
: "Indoleamine 2,3-dioxygenase 1 and programmed cell death-ligand 1 co-expression correlates with aggressive features in lung adenocarcinoma." in: European journal of cancer (Oxford, England : 1990), Vol. 101, pp. 20-29, (2019) (PubMed).: "Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic Cells via Toll-Like Receptors 2 and 4." in: Frontiers in immunology, Vol. 9, pp. 11, (2019) (PubMed).
: "Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium." in: Stem cells international, Vol. 2017, pp. 3215962, (2018) (PubMed).
: "Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition." in: BMC nephrology, Vol. 18, Issue 1, pp. 287, (2017) (PubMed).
: "S100G expression and function in fibroblasts on colitis induction." in: International immunopharmacology, Vol. 39, pp. 92-96, (2017) (PubMed).
: "Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration." in: PLoS ONE, Vol. 12, Issue 6, pp. e0177940, (2017) (PubMed).
: "Expression of indoleamine 2,3-dioxygenase in a murine model of Aspergillus fumigatus keratitis." in: International journal of ophthalmology, Vol. 9, Issue 4, pp. 491-6, (2016) (PubMed).
: "Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes." in: Journal of immunology research, Vol. 2016, pp. 6031486, (2016) (PubMed).
: "1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis." in: Cell death & disease, Vol. 7, Issue 12, pp. e2489, (2016) (PubMed).
: "Indoleamine 2,3-dioxygenase is upregulated in the brain of rats with acute pancreatitis." in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 15, Issue 3, pp. 281-5, (2016) (PubMed).
Synonyms and alternative names related to IDO1
indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 1 L homeolog (ido1.L), indoleamine 2,3-dioxygenase 1 (ido1), indoleamine 2,3-dioxygenase 1 (Ido1), indoleamine 2,3-dioxygenase 1-like (LOC100050681), cd107b, ido, IDO, Ido, IDO-1, IDO1, INDO, indo, IndoProtein level used designations for IDO1
- indoleamine-pyrrole 2,3 dioxygenase
- indoleamine 2,3-dioxygenase 2
- proto-IDO
- putative indoleamine 2,3-dioxygenase
- indoleamine 2,3-dioxygenase 1
- indolamine 2,3 dioxygenase
- indole 2,3-dioxygenase
- indoleamine-pyrrole 2,3-dioxygenase
- IDO-1
- indoleamine 23-dioxygenase
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