IDO Products
(Indoleamine 2,3-Dioxygenase (IDO))
Categories
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].
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Featured IDO Categories
IDO Antibodies
High quality antibodies with extensive validation data.
IDO ELISA Kits
Reliable ELISA kits for a wide range of species.
IDO Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IDO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7433768
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7426307
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN5013734
Quantity
100 μL
Datasheet
Datasheet
Recommended IDO ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (10)
- (6)
Cat. No.
ABIN6574282
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN6730945
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956720
Quantity
96 tests
Datasheet
Datasheet
Recommended IDO Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN6239816
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN4371986
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN4371989
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IDO products
: "Proteinuria is Associated with Urinary Loss of Cubilin and Vitamin D-Binding Protein in Patients with Preeclampsia." in: Scientific reports, Vol. 10, Issue 1, pp. 3956, (2020) (PubMed).: "Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors." in: Journal of neuro-oncology, Vol. 139, Issue 2, pp. 239-249, (2019) (PubMed).
: "Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression." in: International immunopharmacology, Vol. 73, pp. 527-538, (2019) (PubMed).
: "Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma." in: Molecular imaging, Vol. 15, (2016) (PubMed).
: "Respiratory Syncytial Virus-Infected Mesenchymal Stem Cells Regulate Immunity via Interferon Beta and Indoleamine-2,3-Dioxygenase." in: PLoS ONE, Vol. 11, Issue 10, pp. e0163709, (2016) (PubMed).
: "Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection." in: Nature communications, Vol. 6, pp. 8608, (2016) (PubMed).
: "Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes." in: Apoptosis : an international journal on programmed cell death, (2015) (PubMed).
: "Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation." in: Frontiers in oncology, Vol. 5, pp. 87, (2015) (PubMed).
: "Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas." in: Neuro-oncology, Vol. 17, Issue 9, pp. 1284-92, (2015) (PubMed).
: "Human CD14+ CTLA-4+ regulatory dendritic cells suppress T-cell response by cytotoxic T-lymphocyte antigen-4-dependent IL-10 and indoleamine-2,3-dioxygenase production in hepatocellular carcinoma." in: Hepatology (Baltimore, Md.), Vol. 59, Issue 2, pp. 567-79, (2014) (PubMed).
Synonyms and alternative names related to IDO
indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 1 (Ido1), IDO, Ido, IDO-1, INDO, IndoProtein level used designations for IDO
- indolamine 2,3 dioxygenase
- indole 2,3-dioxygenase
- indoleamine-pyrrole 2,3-dioxygenase
- IDO-1
- indoleamine-pyrrole 2,3 dioxygenase
- indoleamine 23-dioxygenase
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