IDH3A Products
(Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008].
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Featured IDH3A Categories
IDH3A Antibodies
High quality antibodies with extensive validation data.
IDH3A ELISA Kits
Reliable ELISA kits for a wide range of species.
IDH3A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IDH3A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN7258018
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN7268029
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN2855763
Quantity
100 μL
Datasheet
Datasheet
Recommended IDH3A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6205396
Quantity
96 tests
Datasheet
Datasheet
Recommended IDH3A Proteins
Latest Publications for our IDH3A products
: "Metabolic reprogramming of cancer-associated fibroblasts by IDH3? downregulation." in: Cell reports, Vol. 10, Issue 8, pp. 1335-48, (2015) (PubMed).: "Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model." in: Environmental toxicology and pharmacology, Vol. 40, Issue 2, pp. 592-9, (2015) (PubMed).
: "Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).
: "Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52146-53, (2003) (PubMed).
: "Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform." in: The Journal of biological chemistry, Vol. 274, Issue 52, pp. 36866-75, (2000) (PubMed).
: "Bovine NAD+-dependent isocitrate dehydrogenase: alternative splicing and tissue-dependent expression of subunit 1." in: Biochemistry, Vol. 39, Issue 7, pp. 1807-16, (2000) (PubMed).
Synonyms and alternative names related to IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha (idh3a), isocitrate dehydrogenase 3 (NAD(+)) alpha (IDH3A), isocitrate dehydrogenase 3 (NAD(+)) alpha (idh3a), isocitrate dehydrogenase 3 (NAD+) alpha S homeolog (idh3a.S), isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), 1110003P10Rik, 1500012E04Rik, AA407078, AI316514, BG1, idh3a, IDH3A, MGC76128, zgc:56380, zgc:85631Protein level used designations for IDH3A
- isocitrate dehydrogenase 3 (NAD+) alpha
- isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
- mitochondrial isocitrate dehydrogenase (nad) subunit alpha
- H-IDH alpha
- NAD(+)-specific ICDH subunit alpha
- NAD(H)-specific isocitrate dehydrogenase alpha subunit
- NAD+-specific ICDH
- isocitrate dehydrogenase (NAD+) alpha chain
- isocitric dehydrogenase subunit alpha
- isocitrate dehydrogenase subunits 3/4
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