For best experience we recommend to activate Javascript in your browser.

IDE Proteins

(Insulin-Degrading Enzyme (IDE))

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009].

recommended

IDE Protein (AA 920-1019) (GST tag) (ABIN1307365)

IDE Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Show Details

recommended

IDE Protein (AA 1-1019) (GST tag) (ABIN1307363)

IDE Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Show Details

recommended

IDE Protein (Myc-DYKDDDDK Tag) (ABIN2723516)

IDE Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Show Details

IDE Proteins by Origin

Find IDE Proteins for a variety of species such as anti-Human IDE, anti-Mouse IDE, anti-Rat IDE. The species listed below are among those available. Click on a link to go to the corresponding products.

IDE Proteins by Source

Here you will find IDE Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IDE Proteins by Protein Type

Here you can find IDE Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IDE Proteins by Application

Find IDE Proteins validated for a specific application such as WB, SDS, ELISA, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular IDE Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

IDE Protein (AA 920-1019) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1307365

Quantity 10 μg

Datasheet Datasheet

IDE Protein (AA 1-1019) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1307363

Quantity 10 μg

Datasheet Datasheet

IDE Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2723516

Quantity 20 μg

Datasheet Datasheet

IDE Protein (AA 753-973) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505065

Quantity 100 μg

Datasheet Datasheet

IDE Protein (AA 42-1019) (His tag)

Reactivity Human

Source Human Cells

Validations

Cat. No. ABIN4370843

Quantity 50 μg

Datasheet Datasheet

IDE Protein (His tag)

Reactivity Human

Source Human Cells

Validations

Cat. No. ABIN7318623

Quantity 50 μg

Datasheet Datasheet

IDE Protein (AA 753-973) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7395194

Quantity 100 μg

Datasheet Datasheet

IDE Protein (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7395197

Quantity 100 μg

Datasheet Datasheet

IDE Protein (AA 1-1019) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3093008

Quantity 1 mg

Datasheet Datasheet

IDE Protein (AA 1-1019) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3137257

Quantity 1 mg

Datasheet Datasheet

IDE Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2750322

Quantity 5 applications

Datasheet Datasheet

IDE Protein (Transcript Variant 1) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2723517

Quantity 10 μg

Datasheet Datasheet

IDE Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6123665

Quantity 100 μg

Datasheet Datasheet

IDE Protein

Reactivity Human

Source

Validations

Cat. No. ABIN622898

Quantity 1 mg

Datasheet Datasheet

IDE Protein

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6380313

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our IDE Proteins

Kim, Lone, Saghatelian: "Analysis of the proteolysis of bioactive peptides using a peptidomics approach." in: Nature protocols, Vol. 8, Issue 9, pp. 1730-42, (2013) (PubMed).

Aliases for IDE Proteins

insulin degrading enzyme (IDE) Proteins
insulin-degrading enzyme (ide) Proteins
insulin-degrading enzyme (LOC591315) Proteins
insulin-degrading enzyme (CC1G_01115) Proteins
insulin-degrading enzyme (Bm1_26615) Proteins
insulin-degrading enzyme (PTRG_10875) Proteins
metallopeptidase (SJAG_01430) Proteins
insulin-degrading enzyme (EBI_21700) Proteins
insulin-degrading enzyme (VDBG_06702) Proteins
insulin-degrading enzyme (LOAG_08082) Proteins
insulin-degrading enzyme (PGTG_04982) Proteins
insulin-degrading enzyme (Tsp_00424) Proteins
insulin degrading enzyme (Ide) Proteins
1300012G03Rik Proteins
4833415K22Rik Proteins
AA675336 Proteins
AI507533 Proteins
IDE Proteins
INSDEGM Proteins
INSULYSIN Proteins
zgc:162603 Proteins

Did you look for something else?

You are here:

IDE Proteins by Origin

IDE Proteins by Source

IDE Proteins by Protein Type

IDE Proteins by Application

Popular IDE Proteins

Latest Publications for our IDE Proteins

Aliases for IDE Proteins

Did you look for something else?

antibodies-online

genomics-online