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Id2 Products

(Inhibitor of DNA Binding 2 (Id2))

Categories

The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011].

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Featured Id2 Categories

Id2 Antibodies

High quality antibodies with extensive validation data.

Id2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Id2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB, FACS
Validations
  • (1)
  • (5)
Cat. No. ABIN1724753
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (6)
Cat. No. ABIN3021262
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (4)
Cat. No. ABIN516796
Quantity 100 μg
Datasheet Datasheet

Recommended Id2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098783
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307351
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307353
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Id2 products

Sa, Hwang, Cho, Ryu, Choi, Jeong, Kim, Kim, Paik, Lee, Choi, Kim, Kim, Bae, Lee, Her, Shin, Cho, Kim, Seo, Koo, Oh, Lee, Kim, Song, Bae, Park, Han, Ahn, Sood, Rabadan, Lee, Nam, Lee: "Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers." in: Genome biology, Vol. 20, Issue 1, pp. 253, (2019) (PubMed).

Goldstein, Goss, Choi, Saur, Seidler, Hare, Chaudhari: "Contribution of Polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT+ culture model and in vivo." in: Development (Cambridge, England), Vol. 143, Issue 23, pp. 4394-4404, (2016) (PubMed).

Liu, Harmelink, Peng, Chen, Wang, Jiao: "CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice." in: Human molecular genetics, Vol. 23, Issue 8, pp. 2145-56, (2014) (PubMed).

Chen, Zhang, Cai, Yao: "ID2: A negative transcription factor regulating oligodendroglia differentiation." in: Journal of neuroscience research, Vol. 90, Issue 5, pp. 925-32, (2012) (PubMed).

Harmelink, Peng, DeBenedittis, Chen, Shou, Jiao: "Myocardial Mycn is essential for mouse ventricular wall morphogenesis." in: Developmental biology, Vol. 373, Issue 1, pp. 53-63, (2012) (PubMed).

Ward, Fernando, Hou, Duffield: "The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 38987-9000, (2010) (PubMed).

Norton, Atherton: "Coupling of cell growth control and apoptosis functions of Id proteins." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).

Norton, Deed, Craggs, Sablitzky: "Id helix-loop-helix proteins in cell growth and differentiation." in: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).

Cooper, Brady, Bilia, Iscove, Quesenberry: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." in: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).

Hara, Hall, Peters: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." in: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).

Synonyms and alternative names related to Id2

inhibitor of DNA binding 2 (Id2), inhibitor of DNA binding 2, HLH protein (Id2), inhibitor of DNA binding 2 (ID2), inhibitor of DNA binding 2 L homeolog (id2.L), Ac2-300, AI255428, bHLHb26, C78922, GIG8, id2-A, ID2A, ID2H, Idb2, XId2

Protein level used designations for Id2

  • DNA-binding protein inhibitor ID-2
  • inhibitor of differentiation 2
  • Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
  • DNA-binding protein inhibitor ID2
  • cell growth-inhibiting gene 8
  • class B basic helix-loop-helix protein 26
  • helix-loop-helix protein ID2
  • DNA-binding protein inhibitor ID-2-A
  • Inhibitor of DNA binding 2-A
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