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IBTK Products

(Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Categories

The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq, Jul 2008].

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Featured IBTK Categories

IBTK Antibodies

High quality antibodies with extensive validation data.

Recommended IBTK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654688
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN952814
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6262431
Quantity 100 μL
Datasheet Datasheet

Recommended IBTK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093014
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135866
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IBTK products

Vecchio, Golino, Pisano, Albano, Falcone, Ceglia, Iaccino, Mimmi, Fiume, Giurato, Britti, Scala, Quinto: "IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis." in: Cell death & disease, Vol. 10, Issue 4, pp. 320, (2019) (PubMed).

Albano, Chiurazzi, Mimmi, Vecchio, Pastore, Cimmino, Frieri, Iaccino, Pisano, Golino, Fiume, Mallardo, Scala, Quinto: "The expression of inhibitor of bruton's tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis." in: Cell death & disease, Vol. 9, Issue 1, pp. 13, (2018) (PubMed).

Willy, Young, Mosley, Gawrieh, Stevens, Masuoka, Wek: "Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response." in: The Journal of biological chemistry, Vol. 292, Issue 34, pp. 14050-14065, (2017) (PubMed).

Synonyms and alternative names related to IBTK

inhibitor of Bruton tyrosine kinase (IBTK), inhibitor of Bruton agammaglobulinemia tyrosine kinase (ibtk), inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk), inhibitor of Bruton tyrosine kinase L homeolog (ibtk.L), inhibitor of Bruton tyrosine kinase (Ibtk), 5430411K16Rik, AA409502, BTBD26, BTKI, DKFZp468J085, fi40c08, IBTK, mKIAA1417, RP1-93K22.1, wu:fi40c08

Protein level used designations for IBTK

  • inhibitor of Bruton agammaglobulinemia tyrosine kinase
  • inhibitor of Bruton's tyrosine kinase
  • inhibitor of Bruton tyrosine kinase-like
  • BTK-binding protein
  • Bruton agammaglobulinemia tyrosine kinase inhibitor
  • inhibitor of Bruton tyrosine kinase
  • inhibitor of Bruton's tyrosine kinase-alpha
  • inhibitor of Bruton's tyrosine kinase-beta
  • inhibitor of Bruton's tyrosine kinase-gamma
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