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Hypoxanthine phosphoribosyltransferase 1 Products

(Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Categories

The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009].

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Featured Hypoxanthine phosphoribosyltransferase 1 Categories

Hypoxanthine phosphoribosyltransferase 1 Antibodies

High quality antibodies with extensive validation data.

Hypoxanthine phosphoribosyltransferase 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Hypoxanthine phosphoribosyltransferase 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Hypoxanthine phosphoribosyltransferase 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7432454
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (6)
Cat. No. ABIN2682995
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN390692
Quantity 400 μL
Datasheet Datasheet

Recommended Hypoxanthine phosphoribosyltransferase 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956643
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956644
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1570337
Quantity 96 tests
Datasheet Datasheet

Recommended Hypoxanthine phosphoribosyltransferase 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667016
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307035
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129775
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Hypoxanthine phosphoribosyltransferase 1 products

Wu, Bond, Chen, Chen, Li, Shohet, Wright: "HIF-1α in the heart: remodeling nucleotide metabolism." in: Journal of molecular and cellular cardiology, Vol. 82, pp. 194-200, (2015) (PubMed).

Magnusson, Strid, Isaksson, Bajor, Lasson, Ung, Öhman: "Response to infliximab therapy in ulcerative colitis is associated with decreased monocyte activation, reduced CCL2 expression and downregulation of Tenascin C." in: Journal of Crohn's & colitis, Vol. 9, Issue 1, pp. 56-65, (2014) (PubMed).

Göttle, Prudente, Fu, Sutcliffe, Pang, Cooper, Veledar, Glass, Gearing, Visser, Jinnah: "Loss of dopamine phenotype among midbrain neurons in Lesch-Nyhan disease." in: Annals of neurology, Vol. 76, Issue 1, pp. 95-107, (2014) (PubMed).

Guibinga, Murray, Barron, Pandori, Hrustanovic: "Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4502-15, (2013) (PubMed).

Hayashi, Naoi, Nakagawa, Nishikawa, Fukuda, Imajoh-Ohmi, Kondo, Kubo, Yabuki, Hattori, Hirouchi, Sugiyama: "Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15054-65, (2012) (PubMed).

Manjanatha, Shelton, Bishop, Shaddock, Dobrovolsky, Heflich, Webb, Blankenship, Beland, Greenlees, Culp: "Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green." in: Mutation research, Vol. 547, Issue 1-2, pp. 5-18, (2004) (PubMed).

Synonyms and alternative names related to Hypoxanthine phosphoribosyltransferase 1

hypoxanthine phosphoribosyltransferase 1 (HPRT1), hypoxanthine guanine phosphoribosyl transferase (Hprt), hypoxanthine phosphoribosyltransferase 1 (Hprt1), hypoxanthine phosphoribosyltransferase 1 (hprt1), hypoxanthine phosphoribosyltransferase 1 L homeolog (hprt1.L), phosphoribosyl transferase domain containing 1 (prtfdc1), C81579, HGPRT, hgprt, Hgprtase, HPGRT, HPRT, Hprt, hprt, Hprt1, hprt1, hprt1l, id:ibd1344, id:ibd5108, prtfdc1, wu:fc10g09, zgc:55561, zgc:56221, zgc:86608, zgc:86771

Protein level used designations for Hypoxanthine phosphoribosyltransferase 1

  • HGPRTase
  • hypoxanthine-guanine phosphoribosyltransferase
  • HGPRT
  • HPRT B
  • hypoxanthine guanine phosphoribosyl transferase 1
  • hypoxanthine phosphoribosyl transferase
  • hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)
  • hypoxanthine phosphoribosyltransferase 1 [(Lesch-Nyhan syndrome)
  • hypoxanthine guanine phosphoribosyl transferase
  • phosphoribosyl transferase domain containing 1
  • HHGP protein
  • hypoxanthine-guanine phosphoribosyltransferase 1
  • hypoxanthine guanine phosphoribosyltransferase 1
  • hypoxanthine-guanine phosphoribosyltransferas-like protein
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