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HYAL1 Products

(Hyaluronidase-1 (HYAL1))

Categories

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured HYAL1 Categories

HYAL1 Antibodies

High quality antibodies with extensive validation data.

HYAL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HYAL1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HYAL1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
  • (1)
Cat. No. ABIN2784342
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (2)
  • (1)
Cat. No. ABIN2784343
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7262501
Quantity 200 μL
Datasheet Datasheet

Recommended HYAL1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956620
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6974238
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956621
Quantity 96 tests
Datasheet Datasheet

Recommended HYAL1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307298
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307300
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN2115435
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our HYAL1 products

Panogeorgou, Tserbini, Filou, Vynios, Naxakis, Papadas, Goumas, Mastronikolis: "Hyaluronan synthases and hyaluronidases in nasal polyps." in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 273, Issue 7, pp. 1801-8, (2016) (PubMed).

Upur, Chen, Kamilijiang, Deng, Sulaiman, Aizezi, Wu, Tulake, Abudula: "Identification of plasma protein markers common to patients with malignant tumour and Abnormal Savda in Uighur medicine: a prospective clinical study." in: BMC complementary and alternative medicine, Vol. 15, pp. 9, (2015) (PubMed).

Papakonstantinou, Roth, Klagas, Karakiulakis, Tamm, Stolz: "COPD exacerbations are associated with pro-inflammatory degradation of hyaluronic acid." in: Chest, (2015) (PubMed).

Rizzardi, Rosener, Koopmeiners, Isaksson Vogel, Metzger, Forster, Marston, Tiffany, McCarthy, Turley, Warlick, Henriksen, Schmechel: "Evaluation of protein biomarkers of prostate cancer aggressiveness." in: BMC cancer, Vol. 14, pp. 244, (2014) (PubMed).

Siiskonen, Poukka, Tyynelä-Korhonen, Sironen, Pasonen-Seppänen: "Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma." in: BMC cancer, Vol. 13, pp. 181, (2013) (PubMed).

Papakonstantinou, Kouri, Karakiulakis, Klagas, Eickelberg: "Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension." in: The European respiratory journal, Vol. 32, Issue 6, pp. 1504-12, (2008) (PubMed).

Daginakatte, Gutmann: "Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth." in: Human molecular genetics, Vol. 16, Issue 9, pp. 1098-112, (2007) (PubMed).

Synonyms and alternative names related to HYAL1

hyaluronoglucosaminidase 1 (HYAL1), hyaluronoglucosaminidase 1 (Hyal1), Hya1, HYAL-1, Hyal-1, LUCA1, NAT6

Protein level used designations for HYAL1

  • hyaluronidase-1
  • luCa-1
  • lung carcinoma protein 1
  • plasma hyaluronidase
  • tumor suppressor LUCA-1
  • hyal-1
  • hyaluronidase 1
  • hyaluronoglucosaminidase-1
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