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HTRA4 Products

(HtrA Serine Peptidase 4 (HTRA4))

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This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008].

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Featured HTRA4 Categories

HTRA4 Antibodies

High quality antibodies with extensive validation data.

HTRA4 ELISA Kits

Reliable ELISA kits for a wide range of species.

HTRA4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HTRA4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
  • (1)
Cat. No. ABIN5675190
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6741359
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN531304
Quantity 50 μg
Datasheet Datasheet

Recommended HTRA4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6956603
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2534589
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5655141
Quantity 96 tests
Datasheet Datasheet

Recommended HTRA4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123368
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307289
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386320
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HTRA4 products

Wang, Li, Hyett, da Silva Costa, Nie: "HtrA3 Isoform-Specific ELISAs for Early Detection of Preeclampsia." in: Journal of biomolecular screening, (2016) (PubMed).

Singh, Zhao, Chen, Wang, Li, Kaituu-Lino, Tong, Nie: "Human HtrA4 Expression Is Restricted to the Placenta, Is Significantly Up-Regulated in Early-Onset Preeclampsia, and High Levels of HtrA4 Cause Endothelial Dysfunction." in: The Journal of clinical endocrinology and metabolism, Vol. 100, Issue 7, pp. E936-45, (2015) (PubMed).

Inagaki, Nishizawa, Ota, Suzuki, Inuzuka, Miyamura, Sekiya, Kurahashi, Udagawa: "Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia." in: Placenta, Vol. 33, Issue 11, pp. 919-26, (2012) (PubMed).

Clausen, Southan, Ehrmann: "The HtrA family of proteases: implications for protein composition and cell fate." in: Molecular cell, Vol. 10, Issue 3, pp. 443-55, (2002) (PubMed).

Synonyms and alternative names related to HTRA4

HtrA serine peptidase 4 (HTRA4), HtrA serine peptidase 4 (Htra4), B430206E18Rik, RGD1306242

Protein level used designations for HTRA4

  • HtrA serine peptidase 4
  • probable serine protease HTRA4-like
  • high-temperature requirement factor A4
  • probable serine protease HTRA4
  • serine protease HTRA4
  • serine protease HTR4
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