HSPG Products
(Heparan Sulphate Protoglycans (HSPG))
Categories
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
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Featured HSPG Categories
HSPG Antibodies
High quality antibodies with extensive validation data.
HSPG ELISA Kits
Reliable ELISA kits for a wide range of species.
HSPG Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSPG Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7432070
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Rat
Application
WB, IHC, IHC (p), IP, ICC, IHC (fro)
Validations
- (2)
Cat. No.
ABIN625887
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Rat
Application
WB, IHC, IHC (p), IP, ICC, IHC (fro)
Validations
- (7)
Cat. No.
ABIN335359
Quantity
0.1 mg
Datasheet
Datasheet
Recommended HSPG ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
Cat. No.
ABIN6954521
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954522
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963169
Quantity
96 tests
Datasheet
Datasheet
Recommended HSPG Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391033
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391036
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3009814
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HSPG products
: "Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass." in: Anaesthesia, Vol. 74, Issue 5, pp. 609-618, (2019) (PubMed).: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).
: "Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro." in: Biomedicine & pharmacotherapy, Vol. 103, pp. 362-372, (2018) (PubMed).
: "Glioma targeting peptide modified apoferritin nanocage." in: Drug delivery, Vol. 25, Issue 1, pp. 1013-1024, (2018) (PubMed).
: "Circulating syndecans during critical illness." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 5, pp. 468-475, (2017) (PubMed).
: "Endothelial glycocalyx layer shedding following lung resection." in: Biomarkers in medicine, Vol. 10, Issue 10, pp. 1033-1038, (2016) (PubMed).
: "Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127584, (2016) (PubMed).
: "Impairment of the endothelial glycocalyx in cardiogenic shock and its prognostic relevance." in: Shock (Augusta, Ga.), Vol. 43, Issue 5, pp. 450-5, (2015) (PubMed).
: "Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme." in: European journal of pharmacology, Vol. 728, pp. 151-60, (2014) (PubMed).
: "Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients." in: Journal of reproductive immunology, Vol. 103, pp. 23-8, (2014) (PubMed).
Synonyms and alternative names related to HSPG
CD44 molecule (Indian blood group) (CD44), glypican 3 (GPC3), CD44 antigen (Cd44), CD44 molecule (Indian blood group) (Cd44), AU023126, AW121933, AW146109, CD44A, CDW44, CSPG8, ECMR-III, HCELL, HERMES, HUTCH-I, IN, LHR, Ly-24, MC56, MDU2, MDU3, METAA, MIC4, Pgp-1, Pgp1, RHAMMProtein level used designations for HSPG
- CD44 antigen
- GP90 lymphocyte homing/adhesion receptor
- Hermes antigen
- cell surface glycoprotein CD44
- chondroitin sulfate proteoglycan 8
- epican
- extracellular matrix receptor III
- hematopoietic cell E- and L-selectin ligand
- heparan sulfate proteoglycan
- homing function and Indian blood group system
- hyaluronate receptor
- phagocytic glycoprotein 1
- ECMR-III
- HUTCH-I
- PGP-I
- hermes antigen
- lymphocyte antigen 24
- phagocytic glycoprotein I
- Cell surface glycoprotein CD44 (hyaluronate binding protein)
- PGP-1
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