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HSPBP1 Products

(HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Categories

Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

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Featured HSPBP1 Categories

HSPBP1 Antibodies

High quality antibodies with extensive validation data.

HSPBP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HSPBP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSPBP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7437581
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7437578
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN525336
Quantity 100 μL
Datasheet Datasheet

Recommended HSPBP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956403
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967467
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5654956
Quantity 96 tests
Datasheet Datasheet

Recommended HSPBP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667132
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307235
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129827
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our HSPBP1 products

Tuo, Shu, She, Yang, Zou, Huang, Hu, Hu, Ren, Peng, Yang: "Sorcin induces gastric cancer cell migration and invasion contributing to STAT3 activation." in: Oncotarget, Vol. 8, Issue 61, pp. 104258-104271, (2017) (PubMed).

Ahn, Park, Choi, Park, Rhee, Kang, Ahn, Lee, Lee, Inn, Cho, Park, Park, Park, Lee, Park, Kwon, Shim, Han, Kim, Lee, Jeon, Huh, Jin, Kim: "Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection." in: Nature microbiology, Vol. 2, pp. 16191, (2016) (PubMed).

Barker, Benovic: "G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4." in: Biochemistry, Vol. 50, Issue 32, pp. 6933-41, (2011) (PubMed).

Raynes, Thomson, Stroster, Newton, Cuneo, Guerriero: "Human serum contains detectable levels of the Hsp70 cochaperone HspBP1 and antibodies bound to HspBP1." in: Journal of immunoassay & immunochemistry, Vol. 27, Issue 3, pp. 251-64, (2006) (PubMed).

Shomura, Dragovic, Chang, Tzvetkov, Young, Brodsky, Guerriero, Hartl, Bracher: "Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange." in: Molecular cell, Vol. 17, Issue 3, pp. 367-79, (2005) (PubMed).

Bernstein, Payne, Kunke, Crowley-Weber, Waltmire, Dvorakova, Holubec, Bernstein, Vaillancourt, Raynes, Guerriero, Garewal: "A proteomic study of resistance to deoxycholate-induced apoptosis." in: Carcinogenesis, Vol. 25, Issue 5, pp. 681-92, (2004) (PubMed).

Alberti, Böhse, Arndt, Schmitz, Höhfeld: "The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator." in: Molecular biology of the cell, Vol. 15, Issue 9, pp. 4003-10, (2004) (PubMed).

McLellan, Raynes, Guerriero: "HspBP1, an Hsp70 cochaperone, has two structural domains and is capable of altering the conformation of the Hsp70 ATPase domain." in: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19017-22, (2003) (PubMed).

Kabani, McLellan, Raynes, Guerriero, Brodsky: "HspBP1, a homologue of the yeast Fes1 and Sls1 proteins, is an Hsc70 nucleotide exchange factor." in: FEBS letters, Vol. 531, Issue 2, pp. 339-42, (2002) (PubMed).

Synonyms and alternative names related to HSPBP1

HSPA (Hsp70) binding protein 1 (HSPBP1), HSPA (Hsp70) binding protein 1 (Hspbp1), HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 (Hspbp1), 1500019G21Rik, FES1

Protein level used designations for HSPBP1

  • Hsp70 binding protein 1
  • heat shock protein-binding protein 1
  • hsp70 interacting protein
  • hsp70-binding protein 1
  • hsp70-binding protein 2
  • hsp70-interacting protein 1
  • hsp70-interacting protein 2
  • hspBP2
  • HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
  • SPA ) binding protein, cytoplasmic cochaperone 1
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