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HSPB8 Products

(Heat Shock 22kDa Protein 8 (HSPB8))

Categories

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008].

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Featured HSPB8 Categories

HSPB8 Antibodies

High quality antibodies with extensive validation data.

HSPB8 ELISA Kits

Reliable ELISA kits for a wide range of species.

HSPB8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSPB8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IP, ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN361852
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN3016167
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP, ICC
Validations
  • (4)
Cat. No. ABIN2486743
Quantity 100 μL
Datasheet Datasheet

Recommended HSPB8 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956392
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956391
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956393
Quantity 96 tests
Datasheet Datasheet

Recommended HSPB8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307223
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307225
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307227
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our HSPB8 products

Webster, Darling, Sanders, Blazier, Vidal-Aguiar, Beaulieu-Abdelahad, Plemmons, Hill, Uversky, Bickford, Dickey, Blair: "Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels." in: International journal of molecular sciences, Vol. 21, Issue 15, (2020) (PubMed).

Chen, Xiang, Gong, Fang, Xu, Zhang, Wu: "Atorvastatin downregulates HSP22 expression in an atherosclerotic model in vitro and in vivo." in: International journal of molecular medicine, Vol. 43, Issue 2, pp. 821-829, (2019) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Irobi, Van Impe, Seeman, Jordanova, Dierick, Verpoorten, Michalik, De Vriendt, Jacobs, Van Gerwen, Vennekens, Mazanec, Tournev, Hilton-Jones, Talbot, Kremensky, Van Den Bosch, Robberecht et al.: "Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. ..." in: Nature genetics, Vol. 36, Issue 6, pp. 597-601, (2004) (PubMed).

Gober, Smith, Ueda, Toretsky, Aurelian: "Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37600-9, (2003) (PubMed).

Depre, Hase, Gaussin, Zajac, Wang, Hittinger, Ghaleh, Yu, Kudej, Wagner, Sadoshima, Vatner: "H11 kinase is a novel mediator of myocardial hypertrophy in vivo." in: Circulation research, Vol. 91, Issue 11, pp. 1007-14, (2002) (PubMed).

Benndorf, Sun, Gilmont, Biederman, Molloy, Goodmurphy, Cheng, Andrews, Welsh: "HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27)." in: The Journal of biological chemistry, Vol. 276, Issue 29, pp. 26753-61, (2001) (PubMed).

Synonyms and alternative names related to HSPB8

heat shock protein family B (small) member 8 (HSPB8), heat shock protein family B (small) member 8 L homeolog (hspb8.L), heat shock protein 8 (hspa8), heat shock protein b8 (hspb8), heat shock protein 8 (Hspb8), heat shock protein family B (small) member 8 (Hspb8), AU018630, AW413033, CMT2L, Cryac, D5Ucla4, DHMN2, E2IG1, fc09c11, H11, H11K, HMN2, HMN2A, hsc70, HSP20-like, HSP22, Hsp22, MGC64408, wu:fb01g06, wu:fc04b04, wu:fc09c11, wu:fi48b06, zgc:64202

Protein level used designations for HSPB8

  • E2-induced gene 1 protein
  • alpha-crystallin C chain
  • heat shock 27kDa protein 8
  • heat shock protein beta-8
  • protein kinase H11
  • small stress protein-like protein HSP22
  • heat shock 22kDa protein 8
  • H11 kinase
  • heat shock 70 kDa protein 8
  • heat shock 70kDa protein 8
  • heat shock cognate 71 kDa protein
  • heat shock cognate 71-kd protein
  • crystallin, alpha C
  • heat shock protein 20-like protein
  • heat shock protein 8
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