HSPB8 Products
(Heat Shock 22kDa Protein 8 (HSPB8))
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The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008].
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Featured HSPB8 Categories
HSPB8 Antibodies
High quality antibodies with extensive validation data.
HSPB8 ELISA Kits
Reliable ELISA kits for a wide range of species.
HSPB8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSPB8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN361852
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN3016167
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, ICC
Validations
- (4)
Cat. No.
ABIN2486743
Quantity
100 μL
Datasheet
Datasheet
Recommended HSPB8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956392
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956391
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956393
Quantity
96 tests
Datasheet
Datasheet
Recommended HSPB8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307223
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307225
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307227
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our HSPB8 products
: "Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels." in: International journal of molecular sciences, Vol. 21, Issue 15, (2020) (PubMed).: "Atorvastatin downregulates HSP22 expression in an atherosclerotic model in vitro and in vivo." in: International journal of molecular medicine, Vol. 43, Issue 2, pp. 821-829, (2019) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. ..." in: Nature genetics, Vol. 36, Issue 6, pp. 597-601, (2004) (PubMed).
: "Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37600-9, (2003) (PubMed).
: "H11 kinase is a novel mediator of myocardial hypertrophy in vivo." in: Circulation research, Vol. 91, Issue 11, pp. 1007-14, (2002) (PubMed).
: "HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27)." in: The Journal of biological chemistry, Vol. 276, Issue 29, pp. 26753-61, (2001) (PubMed).
Synonyms and alternative names related to HSPB8
heat shock protein family B (small) member 8 (HSPB8), heat shock protein family B (small) member 8 L homeolog (hspb8.L), heat shock protein 8 (hspa8), heat shock protein b8 (hspb8), heat shock protein 8 (Hspb8), heat shock protein family B (small) member 8 (Hspb8), AU018630, AW413033, CMT2L, Cryac, D5Ucla4, DHMN2, E2IG1, fc09c11, H11, H11K, HMN2, HMN2A, hsc70, HSP20-like, HSP22, Hsp22, MGC64408, wu:fb01g06, wu:fc04b04, wu:fc09c11, wu:fi48b06, zgc:64202Protein level used designations for HSPB8
- E2-induced gene 1 protein
- alpha-crystallin C chain
- heat shock 27kDa protein 8
- heat shock protein beta-8
- protein kinase H11
- small stress protein-like protein HSP22
- heat shock 22kDa protein 8
- H11 kinase
- heat shock 70 kDa protein 8
- heat shock 70kDa protein 8
- heat shock cognate 71 kDa protein
- heat shock cognate 71-kd protein
- crystallin, alpha C
- heat shock protein 20-like protein
- heat shock protein 8
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