HSP90AA2 Products
(Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2))
Categories
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.
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Featured HSP90AA2 Categories
HSP90AA2 Antibodies
High quality antibodies with extensive validation data.
Recommended HSP90AA2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN361714
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP, IF, ICC
Validations
- (2)
- (2)
Cat. No.
ABIN361664
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN2481336
Quantity
100 μg
Datasheet
Datasheet
Recommended HSP90AA2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (3)
- (1)
Cat. No.
ABIN1686664
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3081550
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2566661
Quantity
0.1 mg
Datasheet
Datasheet
Latest Publications for our HSP90AA2 products
: "Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model." in: PLoS ONE, Vol. 12, Issue 4, pp. e0176747, (2017) (PubMed).: "Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages." in: Journal of leukocyte biology, Vol. 102, Issue 3, pp. 763-774, (2017) (PubMed).
: "17-AAG improves cognitive process and increases heat shock protein response in a model lesion with A?25-35." in: Neuropeptides, Vol. 48, Issue 4, pp. 221-32, (2014) (PubMed).
: "Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells." in: PLoS ONE, Vol. 9, Issue 1, pp. e86842, (2014) (PubMed).
: "Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice." in: PLoS ONE, Vol. 9, Issue 12, pp. e114403, (2014) (PubMed).
: "Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost." in: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 683-93, (2013) (PubMed).
: "Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 31, pp. 12786-91, (2013) (PubMed).
: "The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90." in: Journal of pharmaceutical and biomedical analysis, Vol. 73, pp. 77-81, (2012) (PubMed).
: "Coexposure to mercury increases immunotoxicity of trichloroethylene." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 119, Issue 2, pp. 281-92, (2011) (PubMed).
: "Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp." in: Journal of natural products, Vol. 74, Issue 6, pp. 1491-9, (2011) (PubMed).
Synonyms and alternative names related to HSP90AA2
heat shock protein 90 alpha family class A member 2, pseudogene (HSP90AA2P), HSP90ALPHA, HSPCA, HSPCAL3
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