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HSP90AA2 Products

(Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2))

Categories

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.

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Featured HSP90AA2 Categories

HSP90AA2 Antibodies

High quality antibodies with extensive validation data.

Recommended HSP90AA2 Antibodies

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Reactivity
Application
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Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
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Cat. No. ABIN361714
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, IF, ICC
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Cat. No. ABIN361664
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Cat. No. ABIN2481336
Quantity 100 μg
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Recommended HSP90AA2 Proteins

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Reactivity Human
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Cat. No. ABIN1686664
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3081550
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN2566661
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Latest Publications for our HSP90AA2 products

Deneka, Haber, Kopp, Gaponova, Nikonova, Golemis: "Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model." in: PLoS ONE, Vol. 12, Issue 4, pp. e0176747, (2017) (PubMed).

Bzowska, Nogieć, Bania, Zygmunt, Zarębski, Dobrucki, Guzik: "Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages." in: Journal of leukocyte biology, Vol. 102, Issue 3, pp. 763-774, (2017) (PubMed).

Ortega, Calvillo, Luna, Pérez-Severiano, Rubio-Osornio, Guevara, Limón: "17-AAG improves cognitive process and increases heat shock protein response in a model lesion with A?25-35." in: Neuropeptides, Vol. 48, Issue 4, pp. 221-32, (2014) (PubMed).

Hunter, OHagan, Kenyon, Dhanani, Prinsloo, Edkins: "Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells." in: PLoS ONE, Vol. 9, Issue 1, pp. e86842, (2014) (PubMed).

Smithline, Nikonova, Hensley, Cai, Egleston, Proia, Seeger-Nukpezah, Golemis: "Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice." in: PLoS ONE, Vol. 9, Issue 12, pp. e114403, (2014) (PubMed).

Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: "Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost." in: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 683-93, (2013) (PubMed).

Seeger-Nukpezah, Proia, Egleston, Nikonova, Kent, Cai, Hensley, Ying, Chimmanamada, Serebriiskii, Golemis: "Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 31, pp. 12786-91, (2013) (PubMed).

Bartolini, Wainer, Bertucci, Andrisano: "The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90." in: Journal of pharmaceutical and biomedical analysis, Vol. 73, pp. 77-81, (2012) (PubMed).

Gilbert, Rowley, Gomez-Acevedo, Blossom: "Coexposure to mercury increases immunotoxicity of trichloroethylene." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 119, Issue 2, pp. 281-92, (2011) (PubMed).

Rateb, Houssen, Arnold, Abdelrahman, Deng, Harrison, Okoro, Asenjo, Andrews, Ferguson, Bull, Goodfellow, Ebel, Jaspars: "Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp." in: Journal of natural products, Vol. 74, Issue 6, pp. 1491-9, (2011) (PubMed).

Synonyms and alternative names related to HSP90AA2

heat shock protein 90 alpha family class A member 2, pseudogene (HSP90AA2P), HSP90ALPHA, HSPCA, HSPCAL3
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