HSD17B6 Products
(Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))
Categories
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq, Jul 2008].
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Featured HSD17B6 Categories
HSD17B6 Antibodies
High quality antibodies with extensive validation data.
HSD17B6 ELISA Kits
Reliable ELISA kits for a wide range of species.
HSD17B6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSD17B6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN522080
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN629831
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (2)
- (2)
Cat. No.
ABIN2776865
Quantity
100 μL
Datasheet
Datasheet
Recommended HSD17B6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1742773
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1773677
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Validations
Cat. No.
ABIN1750102
Quantity
96 tests
Datasheet
Datasheet
Recommended HSD17B6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307132
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307130
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2714224
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our HSD17B6 products
: "New insights into diagnosis and therapeutic options for proliferative hepatoblastoma." in: Hepatology (Baltimore, Md.), (2017) (PubMed).: "Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer." in: Cancer research, Vol. 71, Issue 4, pp. 1486-96, (2011) (PubMed).
: "Estrogen receptor ? and 17?-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 50, pp. 20090-4, (2011) (PubMed).
: "Gene structure, chromosomal localization and analysis of 3-ketosteroid reductase activity of the human 3(alpha-->beta)-hydroxysteroid epimerase." in: Biochimica et biophysica acta, Vol. 1520, Issue 2, pp. 124-30, (2001) (PubMed).
Synonyms and alternative names related to HSD17B6
hydroxysteroid 17-beta dehydrogenase 6 (HSD17B6), hydroxysteroid (17-beta) dehydrogenase 6 (Hsd17b6), hydroxysteroid (17-beta) dehydrogenase 6 (HSD17B6), 17betaHSD9, Hsd17b9, HSE, Rdh8, RODH, SDR9C6Protein level used designations for HSD17B6
- 17-beta-HSD 6
- 17-beta-hydroxysteroid dehydrogenase type 6
- 3(alpha->beta)-hydroxysteroid epimerase
- 3(alpha->beta)-hydroxysteroid epimerasel
- 3-alpha->beta-HSE
- 3-alpha->beta-hydroxysteroid epimerase
- 3-hydroxysteroid epimerase
- NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
- hydroxysteroid (17-beta) dehydrogenase 6 homolog
- oxidative 3-alpha hydroxysteroid dehydrogenase
- oxidative 3-alpha-hydroxysteroid-dehydrogenase
- oxidoreductase
- retinol dehydrogenase
- short chain dehydrogenase/reductase family 9C, member 6
- 17-beta-HSD6
- 17-beta-HSD9
- hydroxysteroid (17-beta) dehydrogenase 9
- hydroxysteroid 17-beta dehydrogenase 9
- oxidative 17 beta hydroxysteroid dehydrogenase type 6
- hydroxysteroid 17-beta dehydrogenase 6
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