HSD17B4 Products
(Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
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The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008].
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HSD17B4 Antibodies
High quality antibodies with extensive validation data.
HSD17B4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSD17B4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (1)
- (5)
Cat. No.
ABIN2855717
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (4)
Cat. No.
ABIN2856979
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3031274
Quantity
100 μg
Datasheet
Datasheet
Recommended HSD17B4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3078925
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134367
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Yeast
Validations
- (1)
Cat. No.
ABIN5713516
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HSD17B4 products
: "PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation." in: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 4, (2019) (PubMed).: "Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1514-1524, (2019) (PubMed).
: "Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity. ..." in: Nature communications, Vol. 10, Issue 1, pp. 5291, (2019) (PubMed).
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).
: "Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy." in: Chemico-biological interactions, Vol. 281, pp. 69-80, (2018) (PubMed).
: "Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).
: "Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system." in: Biochimica et biophysica acta, Vol. 1862, Issue 5, pp. 485-495, (2017) (PubMed).
: "Lipid Profile in Human Frontal Cortex is Sustained Throughout Healthy Adult Lifespan to Decay at Advanced Ages." in: The journals of gerontology. Series A, Biological sciences and medical sciences (PubMed).
Synonyms and alternative names related to HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4 (hsd17b4), hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4), peroxisomal Multifunctional enzyme type 2 (Mfe2), hydroxysteroid (17-beta) dehydrogenase 4 (Hsd17b4), hydroxysteroid 17-beta dehydrogenase 4 (Hsd17b4), 4, 17-beta-HSD, 17[b]-HSD, CG3415, DBP, Dmel\\CG3415, DmMFE-2, MFE-2, Mfp-2, MFP2, MPF-2, perMFE-2, PRLTS1, SDR8C1, zgc:55545, zgc:77300Protein level used designations for HSD17B4
- peroxisomal multifunctional enzyme type 2
- CG3415-PA
- Mfe2-PA
- 17-beta-HSD 4
- 17-beta-HSD IV
- 17-beta-hydroxysteroid dehydrogenase 4
- 17beta-estradiol dehydrogenase type IV
- 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
- D-3-hydroxyacyl-CoA dehydratase
- D-bifunctional protein, peroxisomal
- beta-hydroxyacyl dehydrogenase
- beta-keto-reductase
- multifunctional protein 2
- peroxisomal multifunctional protein 2
- short chain dehydrogenase/reductase family 8C, member 1
- D-bifunctional protein
- DBP
- MFE-2
- peroxisomal multifunctional enzyme type II
- 17-beta-hydroxysteroid dehydrogenase type IV
- 17beta-estradiol dehydrogenase
- mutifunctional protein2
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