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Hsc70 Proteins

(Heat Shock 70kDa Protein 8 (HSPA8))

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

recommended

Hsc70 Protein (AA 1-646) (GST tag) (ABIN1307208)

HSPA8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

Hsc70 Protein (His tag) (ABIN1686679)

HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90% WB, SDS, ELISA, Func, AcA Active

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recommended

Hsc70 Protein (AA 359-646) (His tag) (ABIN7123272)

HSPA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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Hsc70 Proteins by Origin

Find Hsc70 Proteins for a variety of species such as anti-Human Hsc70, anti-Rat Hsc70, anti-Chicken Hsc70. The species listed below are among those available. Click on a link to go to the corresponding products.

Hsc70 Proteins by Source

Here you will find Hsc70 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Hsc70 Proteins by Protein Type

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Hsc70 Proteins by Application

Find Hsc70 Proteins validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Hsc70 Proteins by Biological Activity

Find Hsc70 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Hsc70 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Hsc70 Protein (AA 1-646) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1307208

Quantity 10 μg

Datasheet Datasheet

Hsc70 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1686679

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (AA 359-646) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123272

Quantity 50 μg

Datasheet Datasheet

Hsc70 Protein (AA 1-646) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN668046

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (AA 534-615) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397123

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (AA 534-615) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397126

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (AA 534-615) (His tag)

Reactivity Cow

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7400330

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (AA 534-615) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7404647

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (AA 534-615) (His tag)

Reactivity Chicken

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7400333

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7317575

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2129788

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein

Reactivity Cow

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3009779

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3009781

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein

Reactivity Chicken

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3009780

Quantity 100 μg

Datasheet Datasheet

Hsc70 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2723109

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our Hsc70 Proteins

Zhou, Cui, Hu, Wen, Du, Du: "Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease." in: Molecular medicine reports, Vol. 21, Issue 4, pp. 1771-1778, (2020) (PubMed).

Liu, Vielhauer, Holzbeierlein, Zhao, Ghosh, Brown, Lee, Blagg: "KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells." in: Molecular pharmacology, Vol. 88, Issue 1, pp. 121-30, (2015) (PubMed).

Kimura, Yoshikura, Koumura, Hayashi, Kobayashi, Kobayashi, Yano, Inuzuka: "Identification of target antigens of naturally occurring autoantibodies in cerebrospinal fluid." in: Journal of proteomics, (2015) (PubMed).

Ravindran, Bagchi, Inoue, Tsai: "A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane." in: PLoS pathogens, Vol. 11, Issue 8, pp. e1005086, (2015) (PubMed).

Thirunavukarasu, Shi: "An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40." in: Nucleic acid therapeutics, Vol. 25, Issue 2, pp. 103-12, (2015) (PubMed).

Heimdal, Sanchez-Guixé, Aukrust, Bollerslev, Bruland, Jablonski, Erichsen, Gude, Koht, Erdal, Fiskerstrand, Haukanes, Boman, Bjørkhaug, Tallaksen, Knappskog, Johansson: "STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity." in: Orphanet journal of rare diseases, Vol. 9, pp. 146, (2014) (PubMed).

Fujiwara, Furuta, Kikuchi, Aizawa, Hatanaka, Konya, Uchida, Yoshimura, Tamai, Wada, Kabuta: "Discovery of a novel type of autophagy targeting RNA." in: Autophagy, Vol. 9, Issue 3, pp. 403-9, (2013) (PubMed).

Chow, Mok, Xiao, Khalouei, Brown: "Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells." in: Cell stress & chaperones, Vol. 15, Issue 5, pp. 545-53, (2010) (PubMed).

Takino, Kobayashi, Takeuchi: "The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity." in: Journal of gastroenterology, Vol. 45, Issue 6, pp. 646-55, (2010) (PubMed).

Zwang, Hoffert, Pisitkun, Moeller, Fenton, Knepper: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).

Aliases for Hsc70 Proteins

heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) Proteins
heat shock protein family A (Hsp70) member 8 (HSPA8) Proteins
heat shock protein family A (Hsp70) member 8 (Hspa8) Proteins
heat shock 70kDa protein 8 (HSPA8) Proteins
heat shock protein 8 (Hspa8) Proteins
heat shock protein 8 (hspa8) Proteins
2410008N15Rik Proteins
hsc54 Proteins
HSC54 Proteins
hsc70 Proteins
HSC70 Proteins
Hsc70 Proteins
hsc71 Proteins
HSC71 Proteins
Hsc71 Proteins
Hsc73 Proteins
hsp71 Proteins
HSP71 Proteins
hsp73 Proteins
HSP73 Proteins
Hsp73 Proteins
hspa10 Proteins
HSPA10 Proteins
Hspa10 Proteins
lap1 Proteins
LAP1 Proteins
nip71 Proteins
NIP71 Proteins
wu:fb01g06 Proteins
wu:fi48b06 Proteins

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Hsc70 Proteins by Origin

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Hsc70 Proteins by Application

Hsc70 Proteins by Biological Activity

Popular Hsc70 Proteins

Latest Publications for our Hsc70 Proteins

Aliases for Hsc70 Proteins

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