Hsc70 Products
(Heat Shock 70kDa Protein 8 (HSPA8))
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This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Featured Hsc70 Categories
Hsc70 Antibodies
High quality antibodies with extensive validation data.
Hsc70 ELISA Kits
Reliable ELISA kits for a wide range of species.
Hsc70 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Hsc70 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, FACS
Validations
- (9)
Cat. No.
ABIN7154884
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IP, FACS
Validations
- (7)
Cat. No.
ABIN7154883
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ICC, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN2854950
Quantity
100 μL
Datasheet
Datasheet
Recommended Hsc70 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956418
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956420
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956419
Quantity
96 tests
Datasheet
Datasheet
Recommended Hsc70 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1307208
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (6)
Cat. No.
ABIN1686679
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123272
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Hsc70 products
: "Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease." in: Molecular medicine reports, Vol. 21, Issue 4, pp. 1771-1778, (2020) (PubMed).: "Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. ..." in: Nature communications, Vol. 10, Issue 1, pp. 254, (2019) (PubMed).
: "TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging." in: Nature communications, Vol. 10, Issue 1, pp. 3536, (2019) (PubMed).
: "LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding." in: Scientific reports, Vol. 6, pp. 24921, (2018) (PubMed).
: "Oviduct extracellular vesicles protein content and their role during oviduct-embryo cross-talk." in: Reproduction (Cambridge, England), Vol. 154, Issue 3, pp. 153-168, (2017) (PubMed).
: "Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats." in: Biochimica et biophysica acta, Vol. 1861, Issue 7, pp. 1801-1812, (2017) (PubMed).
: "The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 4, pp. 940-951, (2017) (PubMed).
: "Hsc70 facilitates TGF-β-induced activation of Smad2/3 in fibroblastic NRK-49F cells." in: Biochemical and biophysical research communications, Vol. 477, Issue 3, pp. 448-53, (2016) (PubMed).
: "The Molecular Chaperone Hsc70 Interacts with Tyrosine Hydroxylase to Regulate Enzyme Activity and Synaptic Vesicle Localization." in: The Journal of biological chemistry, Vol. 291, Issue 34, pp. 17510-22, (2016) (PubMed).
: "Oxygen-Glucose Deprivation (OGD) Modulates the Unfolded Protein Response (UPR) and Inflicts Autophagy in a PC12 Hypoxia Cell Line Model." in: Cellular and molecular neurobiology, Vol. 36, Issue 5, pp. 701-12, (2016) (PubMed).
Synonyms and alternative names related to Hsc70
heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L), heat shock protein family A (Hsp70) member 8 (HSPA8), heat shock protein family A (Hsp70) member 8 (Hspa8), heat shock 70kDa protein 8 (HSPA8), heat shock protein 8 (Hspa8), heat shock protein 8 (hspa8), 2410008N15Rik, hsc54, HSC54, hsc70, HSC70, Hsc70, hsc71, HSC71, Hsc71, Hsc73, hsp71, HSP71, hsp73, HSP73, Hsp73, hspa10, HSPA10, Hspa10, lap1, LAP1, nip71, NIP71, wu:fb01g06, wu:fi48b06Protein level used designations for Hsc70
- LPS-associated protein 1
- N-myristoyltransferase inhibitor protein 71
- constitutive heat shock protein 70
- heat shock 70kd protein 10
- heat shock cognate 71 kDa protein
- heat shock cognate protein 54
- lipopolysaccharide-associated protein 1
- Hsc70 ATPase
- heat shock 70 kDa protein 8
- heat shock 70kd protein 10 (HSC71)
- heat shock cognate 71 kD protein
- Heat shock cognate protein 70
- heat shock 70kD protein 8
- heat shock protein 8
- heat shock protein A8
- heat shock cognate 70
- heat shock cognate 71 kDa protein-like protein
- heat shock protein 70 cognate
- heat shock cognate hsc73
- heat shock protein cognate 70
- heat shock 70kDa protein 8
- heat shock cognate 71-kd protein
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