HSBP1 Products
(Heat Shock Factor Binding Protein 1 (HSBP1))
Categories
The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor binding protein 1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. During HS response, HSF1 undergoes conformational transition from an inert non-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity. Overexpression of HSBP1 in mammalian cells represses the transactivation activity of HSF1. When overexpressed in C.elegans HSBP1 has severe effects on survival of the animals after thermal and chemical stress consistent with a role of HSBP1 as a negative regulator of heat shock response. [provided by RefSeq, Jul 2008].
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Featured HSBP1 Categories
HSBP1 Antibodies
High quality antibodies with extensive validation data.
HSBP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HSBP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSBP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7154897
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN2606903
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN2606904
Quantity
100 μg
Datasheet
Datasheet
Recommended HSBP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1136204
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1136205
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1136206
Quantity
96 tests
Datasheet
Datasheet
Recommended HSBP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN934887
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307095
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5712057
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HSBP1 products
: "Structure-function analysis of the heat shock factor-binding protein reveals a protein composed solely of a highly conserved and dynamic coiled-coil trimerization domain." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 735-45, (2002) (PubMed).Synonyms and alternative names related to HSBP1
heat shock factor binding protein 1 like 1 (HSBP1L1), heat shock factor binding protein 1 (HSBP1), Heat shock factor binding protein 1 (Bm1_07370), heat shock factor binding protein 1 S homeolog (hsbp1.S), heat shock factor binding protein 1 (hsbp1), heat shock factor binding protein 1 L homeolog (hsbp1.L), heat shock factor binding protein 1 (Hsbp1), heat shock factor binding protein 1b (hsbp1b), 0610007A03Rik, AA408769, HSBP1, hsbp1, hsbp1a, Hsp25, npc-a-13, NPC-A-13, zgc:73224Protein level used designations for HSBP1
- heat shock factor binding protein 1
- Heat shock factor binding protein 1
- heat shock factor-binding protein 1
- heat shock factor binding protein 1 a
- nasopharyngeal carcinoma-associated antigen 13
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