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HRH1 Products

(Histamine Receptor H1 (HRH1))
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

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Featured HRH1 Categories

HRH1 Antibodies

High quality antibodies with extensive validation data.

HRH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HRH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HRH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7155233
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, IHC, IF, FACS
Validations
  • (3)
Cat. No. ABIN185462
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1048957
Quantity 50 μg
Datasheet Datasheet

Recommended HRH1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6967418
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956542
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956543
Quantity 96 tests
Datasheet Datasheet

Recommended HRH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307068
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307067
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408384
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HRH1 products

Suzuki, Ogasawara, Tanaka, Takeda, Sawasaki, Mogi, Liu, Maeyama et al.: "Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with ..." in: Frontiers in pharmacology, Vol. 9, pp. 38, (2018) (PubMed).

Wolak, Bojanowska, Staszewska, Ciosek, Juszczak, Drobnik: "The role of histamine in the regulation of the viability, proliferation and transforming growth factor β1 secretion of rat wound fibroblasts." in: Pharmacological reports : PR, Vol. 69, Issue 2, pp. 314-321, (2017) (PubMed).

Takumida, Takumida, Anniko: "Localization of histamine (H1, H2, H3 and H4) receptors in mouse inner ear." in: Acta oto-laryngologica, Vol. 136, Issue 6, pp. 537-44, (2016) (PubMed).

Girodet, Nguyen, Mancini, Hundal, Zhou, Israel, Cernadas: "Alternative Macrophage Activation Is Increased in Asthma." in: American journal of respiratory cell and molecular biology, Vol. 55, Issue 4, pp. 467-475, (2016) (PubMed).

Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

Møller, Kirkeby, Vikeså, Nielsen, Caye-Thomasen: "Expression of histamine receptors in the human endolymphatic sac: the molecular rationale for betahistine use in Menieres disease." in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, (2015) (PubMed).

Dagli, Goksu, Eryilmaz, Mocan Kuzey, Bayazit, Gun, Gocer: "Expression of histamine receptors (H(1), H(2), and H(3)) in the rabbit endolymphatic sac: an immunohistochemical study." in: American journal of otolaryngology, Vol. 29, Issue 1, pp. 20-3, (2007) (PubMed).

Bryce, Mathias, Harrison, Watanabe, Geha, Oettgen: "The H1 histamine receptor regulates allergic lung responses." in: The Journal of clinical investigation, Vol. 116, Issue 6, pp. 1624-32, (2006) (PubMed).

Sander, Lorentz, Sellge, Coëffier, Neipp, Veres, Frieling, Meier, Manns, Bischoff: "Selective expression of histamine receptors H1R, H2R, and H4R, but not H3R, in the human intestinal tract." in: Gut, Vol. 55, Issue 4, pp. 498-504, (2006) (PubMed).

Kawakami, Miyoshi, Horio, Fukui: "Beta(2)-adrenergic receptor-mediated histamine H(1) receptor down-regulation: another possible advantage of beta(2) agonists in asthmatic therapy." in: Journal of pharmacological sciences, Vol. 94, Issue 4, pp. 449-58, (2004) (PubMed).

Synonyms and alternative names related to HRH1

histamine receptor H1 (HRH1), histamine receptor H1 (Hrh1), histamine receptor H1 (hrh1), histamine receptor H 1 (Hrh1), Bphs, H1, H1-R, H1R, HH1R, Hir, hisH1, Hisr, HRH1

Protein level used designations for HRH1

  • H1R
  • HH1R
  • histamine H(1) receptor
  • histamine H1 receptor
  • histamine receptor, subclass H1
  • Bordetella pertussis induced histamine sensitization
  • histamine receptor subtype H1
  • histamine receptor H1
  • 7 transmembrane receptor
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