HRG Products
(Histidine-Rich Glycoprotein (HRG))
Categories
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Jul 2008].
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Featured HRG Categories
HRG Antibodies
High quality antibodies with extensive validation data.
HRG ELISA Kits
Reliable ELISA kits for a wide range of species.
HRG Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HRG Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7427567
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7440872
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7434977
Quantity
100 μL
Datasheet
Datasheet
Recommended HRG ELISA Kits
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Reactivity
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Human
Analytical Method
Quantitative Sandwich ELISA
Validations
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- (6)
Cat. No.
ABIN6720587
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956556
Quantity
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Datasheet
Datasheet
Reactivity
Mouse
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Validations
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Cat. No.
ABIN6967423
Quantity
96 tests
Datasheet
Datasheet
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Source
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- (1)
Cat. No.
ABIN1307066
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7504420
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413226
Quantity
100 μg
Datasheet
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Latest Publications for our HRG products
: "Ultrastructural Localization of Histidine-rich Glycoprotein in Skeletal Muscle Fibers: Colocalization With AMP Deaminase." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 68, Issue 2, pp. 139-148, (2020) (PubMed).: "Combination of serum histidine-rich glycoprotein and uterine artery Doppler to predict preeclampsia." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 41, Issue 4, pp. 275-281, (2018) (PubMed).
: "Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice." in: Nucleic acid therapeutics, Vol. 26, Issue 4, pp. 223-35, (2016) (PubMed).
: "The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein." in: International journal of cancer. Journal international du cancer, Vol. 136, Issue 11, pp. 2693-704, (2015) (PubMed).
: "New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2015) (PubMed).
: "Evaluation of histidine-rich glycoprotein tissue RNA and serum protein as novel markers for breast cancer." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 4, pp. 897, (2014) (PubMed).
: "Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes." in: PLoS ONE, Vol. 9, Issue 9, pp. e107483, (2014) (PubMed).
: "P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid." in: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17318-30, (2012) (PubMed).
: "Prediction of preeclampsia by combining serum histidine-rich glycoprotein and uterine artery Doppler." in: American journal of hypertension, Vol. 25, Issue 12, pp. 1305-10, (2012) (PubMed).
: "Identification and confirmation of differentially expressed fucosylated glycoproteins in the serum of ovarian cancer patients using a lectin array and LC-MS/MS." in: Journal of proteome research, Vol. 11, Issue 9, pp. 4541-52, (2012) (PubMed).
Synonyms and alternative names related to HRG
histidine rich glycoprotein (HRG), histidine-rich glycoprotein (LOAG_12427), histidine-rich glycoprotein (LOC100597044), histidine-rich glycoprotein (Hrg), AI265597, AW413091, D16jh2, D18020, Hprg, HPRG, HRG1, Hrgp, HRGP, THPH11Protein level used designations for HRG
- histidine-rich glycoprotein
- histidine-proline-rich glycoprotein
- histidine-rich glycoprotein 1
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