HPSE Products
(Heparanase (HPSE))
Categories
Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
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Featured HPSE Categories
HPSE Antibodies
High quality antibodies with extensive validation data.
HPSE ELISA Kits
Reliable ELISA kits for a wide range of species.
HPSE Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HPSE Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7438439
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7437449
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7438010
Quantity
100 μL
Datasheet
Datasheet
Recommended HPSE ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN6574194
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (5)
Cat. No.
ABIN6730979
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967351
Quantity
96 tests
Datasheet
Datasheet
Recommended HPSE Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Synthetic
Validations
- (3)
Cat. No.
ABIN1880256
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7490767
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307050
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our HPSE products
: "Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability." in: Nature communications, Vol. 8, Issue 1, pp. 1323, (2018) (PubMed).: "Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage." in: Renal failure, Vol. 39, Issue 1, pp. 698-701, (2018) (PubMed).
: "Evaluation of the C-domain of heparanase during AGE-induced macrophage inflammatory response." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 1017-1022, (2017) (PubMed).
: "PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection." in: Tumour biology, Vol. 37, Issue 3, pp. 2987-98, (2016) (PubMed).
: "Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury." in: PLoS ONE, Vol. 11, Issue 7, pp. e0160074, (2016) (PubMed).
: "Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop." in: Oncotarget, Vol. 7, Issue 39, pp. 63324-63337, (2016) (PubMed).
: "Serum heparanase concentration and heparanase activity in patients with retinal vein occlusion." in: Acta ophthalmologica, Vol. 95, Issue 1, pp. e62-e66, (2016) (PubMed).
: "High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression." in: Journal of cellular and molecular medicine, Vol. 19, Issue 6, pp. 1366-74, (2015) (PubMed).
: "Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 6, pp. 1850-62, (2015) (PubMed).
: "Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4903-12, (2015) (PubMed).
Synonyms and alternative names related to HPSE
heparanase (HPSE), heparanase (hpse), heparanase (Hpse), Hep, hpa, HPA, Hpa, hpa1, HPA1, hpr1, HPR1, Hpr1, HPSE, hpse1, HPSE1, hse1, HSE1, im:7144134Protein level used designations for HPSE
- heparanase
- endo-glucoronidase
- heparanase-1
- endoglycosidase heparanase
- heparanase-like
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