Recognize C-terminal, internal and N-terminal Protein C epitope (EDQVDPRLIDGK) tagged proteins.
Immunogen
A synthetic peptide CEDQVDPRLIDGK conjugated to KLH.
Isotype
IgG1
Application Notes
WB (1:1000-10,000). Other applications have not been tested. The optimal dilutions should be determined by end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS (pH7.4), 50% Glycerol and 0.02% Sodium Azide.
Preservative
Sodium azide, Thimerosal (Merthiolate)
Storage
-20 °C
Storage Comment
Store at -20 °C for 1 year. Or aliquot and store at -80 °C for long term. Avoid repeated freeze and thaw cycles.
Expiry Date
12 months
Target
HPC4
(Prostate Cancer, Hereditary, 4 (HPC4))
Alternative Name
HPC4
Background
Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death, and maintaining the permeability of blood vessel walls in humans and other animals. The zymogenic form of protein C is a vitamin K-dependent glycoprotein that circulates in blood plasma. Its structure is that of a two-chain polypeptide consisting of a light chain and a heavy chain connected by a disulfide bond. Protein C Tag (HPC4) is a 12 amino acid sequence EDQVDPRLIDGK, which encodes residues 6 through 17 of the heavy chain of the protein.Protein C Tag Antibody is a useful tool in analysis of Protein C fusion proteins.